Results 41 to 50 of about 173,472,529 (256)

Factors Associated with the Failed Induction of Labour in Post-Term Pregnancy at a Tertiary Care Hospital in Karachi, Pakistan

Journal of the Dow University of Health Sciences, 2017
Objective: To determine the factors associated with failed induction of labour in post-term pregnancies attending a tertiary care hospital in Karachi, Pakistan.
Pushpa Makhijani, Sarah kazi, Syeda Rabia   +2 more
doaj   +4 more sources

MATERNAL OBESITY AND OBSTETRIC OUTCOME IN PREGNANT WOMEN ATTENDING PNS SHIFA KARACHI

Pakistan Armed Forces Medical Journal, 2021
Objective: To evaluate the impact of obesity on maternal and neonatal outcome. Study Design: Comparative cross sectional study. Place and Duration of Study: Department of Gynaecology and Obstetrics, Pakistan Naval Ship, Shifa Hospital Karachi ...
Rabiah Anwar, Kashif Razzaq, Naheed Parveen   +2 more
doaj   +1 more source

Predicting the Antepartum Factors Resulted in Failed Labor Induction in Nulliparous Term Pregnancies

Fertility, Gynecology and Andrology, 2021
Objectives: This study aimed to evaluate the feasibility of using a computerized machine to predict a successful normal vaginal delivery and determine the antepartum factors involved in failed labor induction in nulliparous term women. Methods: This prospective cohort study was conducted in Yas Hospital affiliated with Tehran University of Medical ...
Mahboobeh Shirazi, Batool Ghorbani Yekta, Mansour Shamsipour, Shirin Kharazi Kalejahi, Marjan Ghaemi   +4 more
openaire   +2 more sources

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Effect of extra-amniotic Foley’s catheter and vaginal misoprostol versus vaginal misoprostol alone on cervical ripening and induction of labor in Kenya, a randomized controlled trial

BMC Pregnancy and Childbirth, 2018
Background The safest, most effective and fastest combined approaches to induction of labor is unknown. In an open-label randomized clinical trial we evaluated the efficacy of combination of extra-amniotic Foley’s catheter and vaginal misoprostol ...
Alfred Osoti, Davies Kiprop Kibii, Tito Mario Kual Tong, Innocent Maranga   +3 more
doaj   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Failed induction of labor and associated factors among women undergoing induction of labor

International Journal of Reproduction, Contraception, Obstetrics and Gynecology
Background: Induction of labor (IOL) is increasingly employed in modern obstetric care, yet carries a significant risk of failure, contributing to higher caesarean rates and associated maternal-neonatal morbidity. Identifying factors that influence IOL success is essential for individualized labor management.
Gayatri L. Patil, Tejaswi V. Pujar, Pooja Hombardi, Veda R.   +3 more
openaire   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source