Results 211 to 220 of about 8,959,179 (357)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Exploring Macrophage Polarization and Immune Response Dynamics: The Impact of mature Cardiolipin in a TAFAZZIN-Deficient Model

open access: yesJournal of Molecular and Cellular Cardiology Plus
Katharina Ermer   +6 more
doaj   +1 more source

Influence of k-wire placement on impact mechanics and bone fracture in a rabbit model of cartilage injury. [PDF]

open access: yesPLoS One
Noori-Dokht H   +6 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

A higher posterior tibial slope and tunnel malposition do not predispose to non-traumatic anterior cruciate ligament failure. [PDF]

open access: yesJ Exp Orthop
Fritsch L   +7 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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