Results 171 to 180 of about 15,405,604 (296)

Multiscale Damage and Failure Behavior of Drainage Asphalt Mixture Under Multifactor. [PDF]

Materials (Basel)
Tao X, Bai T, Fan J, Shen H, Cheng H.
europepmc   +1 more source

Study on Mechanical Failure Behavior of Steel-Wire Wound Reinforced Thermoplastic Pipe under Combined Internal Pressure and Soil Landslide Conditions. [PDF]

Materials (Basel), 2023
Shi J, Hu Z, Zeng L, Lu P, Chen H, Yu N, Li X.   +6 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Effect of Thickness on the Uniaxial Compression Failure Behavior of CFRP Laminates. [PDF]

Polymers (Basel)
Qin Z, Ding H, Zhu S, Jin C, Wang J, Li J, Wang H.   +6 more
europepmc   +1 more source

Effect of Defects on Progressive Failure Behavior of Plain Weave Textile Composites. [PDF]

Materials (Basel), 2021
Woo K, Lim JH, Han C.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Study on the damage and failure behavior of coal exposed to acid corrosion under impact load. [PDF]

PLoS One
Chen Z, Han W, Zheng X, Liu H.
europepmc   +1 more source

Effect of Particle Size Distributions and Shapes on the Failure Behavior of Dry Coke Aggregates. [PDF]

Materials (Basel), 2021
Sadeghi-Chahardeh A, Mollaabbasi R, Picard D, Taghavi SM, Alamdari H.   +4 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

"Observability and Overcoming Coordination Failure in Organizations" [PDF]

Many organizations suffer poor performance because its members fail to coordinate on efficient patterns of behavior. In previous research, we have shown that financial incentives can be used to find a way out of such performance traps.
David J. Cooper, Jordi Brandts
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