Results 161 to 170 of about 8,475,956 (306)

Generative Modeling for Interpretable Anomaly Detection in Medical Imaging: Applications in Failure Detection and Data Curation. [PDF]

Bioengineering (Basel)
Woodland ME, Altaie M, O'Connor CS, Castelo AH, Lebimoyo OC, Gupta AC, Yung JP, Kinahan PE, Fuller CD, Koay EJ, Odisio BC, Patel AB, Brock KK.   +12 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Failure Detection in Sensors via Variational Autoencoders and Image-Based Feature Representation. [PDF]

Sensors (Basel)
Moreno Haro LM, Oliveira-Filho A, Agard B, Tahan A.   +3 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Enhancing heart failure detection and patient engagement with the Maastricht Decompensation Questionnaire. [PDF]

Neth Heart J
Gingele AJ, Brunner-La Rocca HP.
europepmc   +1 more source

Usefulness of heart rhythm complexity in heart failure detection and diagnosis. [PDF]

Sci Rep, 2020
Tsai CH, Ma HP, Lin YT, Hung CS, Huang SH, Chuang BL, Lin C, Lo MT, Peng CK, Lin YH.   +9 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

A Novel, Non-Invasive AI-Based Telemonitoring System for Heart Failure: Detection of Undiagnosed Hyperthyroidism in an Asymptomatic Patient. [PDF]

Eur J Case Rep Intern Med
Böhm A, Lucka J, Segev A, Kollarova M, Toth S, Jajcay N, Bezak B.   +6 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Investigating the Impact of the Stationarity Hypothesis on Heart Failure Detection using Deep Convolutional Scattering Networks and Machine Learning. [PDF]

Sci Rep
Ait Bourkha ME, Nasir D.
europepmc   +1 more source