Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
Study on nutritional status and incidence of sarcopenia in elderly patients with chronic heart failure. [PDF]
Song S, Du H, Lu X, Luo B, Li Z.
europepmc +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD
ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock +4 more
wiley +1 more source
When ICDs Do Not Deliver: The Unseen Burden of Untreated Arrhythmias. [PDF]
Monkhouse C +5 more
europepmc +1 more source
DIA-Estimator and Multidimensional Model Misspecifications: GNSS-based Positioning Safety Analysis for UAV. [PDF]
Ciuban S, Teunissen PJG, Tiberius CCJM.
europepmc +1 more source
Mortality surveillance as an early warning system for respiratory infection outbreaks: lessons from the COVID-19 pandemic in Alexandria, Egypt. [PDF]
Meckawy R +3 more
europepmc +1 more source
Bridging innovation and access: integrating cardiac amyloidosis into health system strengthening in the Americas. [PDF]
Zavaleta-Monestel E +3 more
europepmc +1 more source
Albumin-corrected calcium ratios for citrate accumulation increase detection and improve mortality prediction in continuous kidney replacement therapy. [PDF]
Khawaja I +6 more
europepmc +1 more source

