Results 121 to 130 of about 2,619,969 (311)

Faulty sensor detection mechanism using multi-variate sensors in IoT [PDF]

open access: yes, 2019
Internet of Thing (IoT) becoming increasingly popular over the past few years because it can be implemented in many applications such as smart cities, smart agriculture, smart health, smart home and etc.
Al-Atrakchii, Khaldoon Ammar
core   +1 more source

Mechanism for the failure of the Edwards hypothesis in the SK spin glass

open access: yes, 2006
The dynamics of the SK model at T=0 starting from random spin configurations is considered. The metastable states reached by such dynamics are atypical of such states as a whole, in that the probability density of site energies, $p(\lambda)$, is small at
A. J. Bray   +5 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

An experimental and finite element study of the low-cycle fatigue failure of a galvanised steel lighting column [PDF]

open access: yes, 2009
This paper presents the results of a low-cycle fatigue test on a lighting column. The wind induced vibration phenomena responsible for low cycle fatigue in such structures is discussed and the failure mechanism is examined.
Alexander, Louise A.   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The Failure Mechanics of Dealer Banks [PDF]

open access: yesSSRN Electronic Journal, 2009
During the recent financial crisis, major dealer banks—that is, banks that intermediate markets for securities and derivatives—suffered from new forms of bank runs. The most vivid examples are the 2008 failures of Bear Stearns and Lehman Brothers.
openaire   +4 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A new engineering approach to predict the hydrostatic strength of uPVC\ud pipes [PDF]

open access: yes, 2007
Extruded unplasticised Poly(Vinyl Chloride) (uPVC) pipes are certified using pressurised pipe tests.\ud During these tests the pipes are subjected to a certain temperature and internal pressure, while the\ud time-to-failure, the time at which the ...
Bor, T.C.   +3 more
core   +2 more sources

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