Results 221 to 230 of about 5,959,491 (252)

Investigation on Mechanical Properties, Damage Forms, and Failure Mechanisms of Additively Manufactured Schoen Gyroid TPMS Porous Structures Under Compressive Load. [PDF]

Materials (Basel)
Hou Y, Cai X, Zhang W, Liu B, Mu Z, Wang J, Han L, Xie W, Sun H.   +8 more
europepmc   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Reinforced Concrete Beams with FRP and Hybrid Steel-FRP Composite Bars: Load-Deflection Response, Failure Mechanisms, and Design Implications. [PDF]

Materials (Basel)
Dziomdziora P, Smarzewski P.
europepmc   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Review of Failure Mechanisms of Steel Wire Ropes Under Heavy-Load Conditions and the Anti-Friction Effects of Gel-like Grease. [PDF]

Gels
Peng H, Zhang Y, Shangguan L, Zhao M, Li B, Yang L, Liu Y.   +6 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

NAD metabolism and heart failure: Mechanisms and therapeutic potentials. [PDF]

J Mol Cell Cardiol
Walker MA, Tian R.
europepmc   +1 more source

Machine learning of automatic hierarchical multi-label classification method for identifying metal failure mechanisms. [PDF]

Sci Rep
Han R, Liu CB, Sun W, Yu S, Zheng H, Deng L.   +5 more
europepmc   +1 more source

Deformation and Failure Mechanisms of Natural/Waste Rubber Blends Under Mechanical and Thermal Cycles: A Synchrotron In Situ Study. [PDF]

Macromol Rapid Commun
Uliana S, Candau N, Arioli M, Franco L, Maspoch ML.   +4 more
europepmc   +1 more source