Thermal barrier coating life prediction model development [PDF]
In order to fully exploit thermal barrier coatings (TBCs) on turbine components and achieve the maximum performance benefit, the knowledge and understanding of TBC failure mechanisms must be increased and the means to predict coating life developed.
Hillery, R. V.
core +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Research of IGBT Module Application Failure for Locomotive
Aiming at the problem of explosion damage of IGBT module used in locomotive after application failure, which makes it difficult to find the failure reason.
Min'an LIU, Hua XIANG, Libin XU, Yao MA
doaj
A dual-mode generalized likelihood ratio approach to self-reorganizing digital flight control system design [PDF]
The research is reported on the problems of failure detection and reliable system design for digital aircraft control systems. Failure modes, cross detection probability, wrong time detection, application of performance tools, and the GLR computer ...
Bueno, R. +3 more
core +1 more source
Fractography can be used to analyze failure modes in polytetrafluoroethylene [PDF]
Fractographic principles used for analyzing failure in metals are applied to the analysis of the microstructure and fracture of polytetrafluoroethylene.
Nerren, B. H.
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Program in electro-physical studies - Microcircuit models and diagnostic techniques for environmental failure mode prediction [PDF]
Microcircuit models and computer program for predicting failure modes under adverse environmental ...
Herskowitz, G. J. +2 more
core +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Tensile failure criteria for fiber composite materials [PDF]
The analysis provides insight into the failure mechanics of these materials and defines criteria which serve as tools for preliminary design material selection and for material reliability assessment. The model incorporates both dispersed and propagation
Rosen, B. W., Zweben, C. H.
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source

