Results 121 to 130 of about 962,464 (311)

Thermal barrier coating life prediction model development [PDF]

open access: yes, 1984
In order to fully exploit thermal barrier coatings (TBCs) on turbine components and achieve the maximum performance benefit, the knowledge and understanding of TBC failure mechanisms must be increased and the means to predict coating life developed.
Hillery, R. V.
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Research of IGBT Module Application Failure for Locomotive

open access: yes机车电传动, 2020
Aiming at the problem of explosion damage of IGBT module used in locomotive after application failure, which makes it difficult to find the failure reason.
Min'an LIU, Hua XIANG, Libin XU, Yao MA
doaj  

A dual-mode generalized likelihood ratio approach to self-reorganizing digital flight control system design [PDF]

open access: yes
The research is reported on the problems of failure detection and reliable system design for digital aircraft control systems. Failure modes, cross detection probability, wrong time detection, application of performance tools, and the GLR computer ...
Bueno, R.   +3 more
core   +1 more source

Fractography can be used to analyze failure modes in polytetrafluoroethylene [PDF]

open access: yes, 1969
Fractographic principles used for analyzing failure in metals are applied to the analysis of the microstructure and fracture of polytetrafluoroethylene.
Nerren, B. H.
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Program in electro-physical studies - Microcircuit models and diagnostic techniques for environmental failure mode prediction [PDF]

open access: yes
Microcircuit models and computer program for predicting failure modes under adverse environmental ...
Herskowitz, G. J.   +2 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Tensile failure criteria for fiber composite materials [PDF]

open access: yes
The analysis provides insight into the failure mechanics of these materials and defines criteria which serve as tools for preliminary design material selection and for material reliability assessment. The model incorporates both dispersed and propagation
Rosen, B. W., Zweben, C. H.
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

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