Results 111 to 120 of about 4,461,053 (307)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Predicting of parameters of reliability two-cascade thermoelectrical cooling device in a mode Q0max [PDF]
Tekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2009 The parities for an estimation of parameters of reliability two-cascade ТED of a various design depending on their basic parameters in a mode Q0max are received.
Khramova L. F. +3 more
doaj
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Frontiers in MedicineBackgroundThe conventional midline approach for lumbar puncture (MAT-LP) has a relatively low success rate of 70%. The paramedian approach can increase the effective puncture area and success rate but lacks standardized guidelines. This study evaluated a
Yuan-Dong Zhuang +7 more
doaj +1 more source
Asymptotic behavior of mixture failure rates [PDF]
Mixtures of increasing failure rate distributions (IFR) can decrease at least in some intervals of time. Usually this property is observed asymptotically as time tends to infinity , which is due to the fact that a mixture failure rate is ‘bent down’, as ...
Maxim S. Finkelstein, Veronica Esaulova
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Discontinuities in regularised media [PDF]
, 2003 Discontinuous interpolation of the problem fields in non-local and rate-dependent media is considered. The necessity of discontinuities in the analysis of failure processes and some of the requirements for the introduction of discontinuities in ...
Simone, A, Sluys, LJ, Wells, GN
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
A New One-Parameter Model by Extending Maxwell–Boltzmann Theory to Discrete Lifetime Modeling
MathematicsThe Maxwell–Boltzmann (MB) distribution is fundamental in statistical physics, providing an exact description of particle speed or energy distributions.
Ahmed Elshahhat +2 more
doaj +1 more source
The financial sustainability of Microcredit in Portugal [PDF]
Microcredit and microfinance emerged in the 1970’s in Bangladesh and other developing countries and expanded rapidly worldwide as a business model financially sustainable and able to fight poverty and social exclusion.
Isabel G Mota +2 more
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