Results 191 to 200 of about 4,436,913 (350)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Comparative evaluation of bonding failure rate with two light cure orthodontic adhesives: a cross-arch split-mouth prospective study. [PDF]

Dental Press J Orthod
Jain D, Chopra SS, Thakur VK, Sewda SK.
europepmc   +1 more source

A novel artificial vertebral implant with Gyroid porous structures for reducing the subsidence and mechanical failure rate after vertebral body replacement. [PDF]

J Orthop Surg Res, 2023
Shang P, Ma B, Hou G, Zhang Y, Cui L, Song W, Liu Y.   +6 more
europepmc   +1 more source

Failure rate of a rotating hinge knee design due to yoke fracture of the hinged tibial insert: a retrospective data analysis and review of the literature [PDF]

, 2011
Joerg Friesenbichler, Ran Schwarzkopf, Patrick Sadoghi, Scott Marwin, Mathias Glehr, Werner Maurer-Ertl, Andreas Leithner   +6 more
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Failure rate and complications of small-bore, wire-guided chest drains in adult patients presenting with traumatic and nontraumatic pleural diseases: A systematic review. [PDF]

Qatar Med J
Alomar Z, Tawfek Z, Alomar Y, Mahmood I, Alomar A, El-Menyar A, Rizoli S, Al-Thani H.   +7 more
europepmc   +1 more source

Survival Rate of Chronic Obstructive Pulmonary Disease Patients with Type II Respiratory Failure at Haji Adam Malik Hospital

Putri Nahrisyah, Fajrinur Syahrani, Amira Permatasari Tarigan, Taufik Ashar   +3 more
openalex   +1 more source

Heart Rate or Beta-Blocker Dose? Association With Outcomes in Ambulatory Heart Failure Patients With Systolic Dysfunction

, 2015
Mona Fiuzat, Daniel Wojdyla, Ileana L. Piña, Kirkwood F. Adams, David J. Whellan, Christopher M. O’Connor   +5 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Saving the Meniscus: A Retrospective Observational Study of the Incidence, Treatment, and Failure Rate of the Main Meniscal Tear Types at 24-Month Follow-Up. [PDF]

J Clin Med
Screpis D, Qordja F, De Berardinis L, Piovan G, Magnanelli S, Amarossi A, Gigante AP, Zorzi C.   +7 more
europepmc   +1 more source