Results 81 to 90 of about 45,359 (268)

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Predicting of parameters of reliability two-cascade thermoelectrical cooling device in a mode Q0max [PDF]

open access: yesTekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2009
The parities for an estimation of parameters of reliability two-cascade ТED of a various design depending on their basic parameters in a mode Q0max are received.
Khramova L. F.   +3 more
doaj  

METHODOLOGY OF DETERMINING THE PARAMETERS OF TRACTION ELECTRIC MOTOR FAILURES WHEN OPERATING TROLLEYBUSES

open access: yesNauka ta progres transportu, 2018
Purpose. The work is aimed to study the change in parameters of traction electric motors of trolleybuses during operation and improvement of the technical state control system, using modern diagnostic methods. Methodology.
Т. P. Pavlenko   +3 more
doaj   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Reliability Assessment of an Improved Single‐Input Switched‐Capacitor Boost 7/9‐Level Inverter Suitable for Renewable Energies

open access: yesEngineering Reports
This paper proposes an improved single‐source switched‐capacitor inverter that can operate either as 7 or 9‐level inverter based on its capacitors' charging scenario.
Armin Ghelichi   +2 more
doaj   +1 more source

Possibilities of realization of the failure analysis method for machines

open access: yesVojnotehnički Glasnik, 2001
In this paper, on the basis of the known methods of failure analysis developed primarily for electronic devices FMEA and FMECA, the possibility of their application on a complex machine conditioned the development of an 'adjusted' method of the working ...
Petar Gardijan
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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