Results 81 to 90 of about 4,461,053 (307)

Properties of distributions with increasing failure rate [PDF]

open access: yes
This paper solves the search for interior solutions to optimization problems using stochastic variables. This is done by way of some new properties of distribution functions with increasing failure rates as characterized in Barlow and Proschan (1965 ...
Brusset, Xavier
core   +1 more source

A new engineering approach to predict the hydrostatic strength of uPVC\ud pipes [PDF]

open access: yes, 2007
Extruded unplasticised Poly(Vinyl Chloride) (uPVC) pipes are certified using pressurised pipe tests.\ud During these tests the pipes are subjected to a certain temperature and internal pressure, while the\ud time-to-failure, the time at which the ...
Bor, T.C.   +3 more
core   +2 more sources

Fracture size effects in nanoscale materials: the case of graphene

open access: yes, 2015
Nanoscale materials display enhanced strength and toughness but also larger fluctuations and more pronounced size effects with respect to their macroscopic counterparts.
Sellerio, Alessandro Luigi   +2 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Completely monotone regression estimates of software failure rates [PDF]

open access: yes
A method for estimating the present failure rate of a program is presented. A crude nonparameter estimate of the failure rate function is obtained from past failure times.
Miller, D. R., Sofer, A.
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Remote operation of an orbital maneuvering vehicle in simulated docking maneuvers [PDF]

open access: yes
Simulated docking maneuvers were performed to assess the effect of initial velocity on docking failure rate, mission duration, and delta v (fuel consumption).
Brody, Adam R.
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Standardization of cumulative failure rates [PDF]

open access: yesDemography, 1975
Abstract A method is proposed for standardizing life table cumulative failure rates for various cohorts so that they are adjusted to the distribution of exposure by age group for a particular cohort. An approximate standard error for the standardized cumulative failure rate is presented. Application of the methodology is illustrated by a
openaire   +2 more sources

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