Results 51 to 60 of about 478,344 (266)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Publication of Atmospheric Model Data using the ATMODAT Standard
Meteorologische Zeitschrift, 2022 Scientific data should be published in a way so that other scientists can benefit from these data, enabling further research. The FAIR Data Principles are defining the basic prerequisite for a good data publication: data should be Findable, Accessible ...
Anette Ganske +4 more
doaj +1 more source
, 1995 Pourquoi faire appel aux services de « Pizza express » le jeudi et préparer des confitures maison le dimanche ? Quelles tâches sont effectuées au sein de la famille et quelles autres sont confiées à l'extérieur ? Quel est le rôle des réseaux de parenté ? Comment s'organisent les relations entre un ménage et les personnes qu'il emploie ?
openaire +3 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FaN-REMs: Fair and Normalized Retrieval Evaluation Metrics for Learning Retrieval Systems
IEEE AccessRetrieval evaluation metrics are vital for resilient artificial intelligence (AI) retrieval systems and its subfields, such as case-based reasoning (CBR).
Amar Jaiswal +3 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
FAIRS, FORMS OF EXPRESSION OF THE LOCAL IDENTITY CASE STUDY: BEIUȘ FAIR, BIHOR COUNTY, ROMANIA [PDF]
Analele Universităţii din Oradea: Seria Geografie, 2017 This study dwells on the role and the importance of fairs, and particularly about ”Beiuș Fair”, in conserving, promoting and capitalizing the identity of the local elements.
Grigore Vasile HERMAN +1 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source