Results 151 to 160 of about 833,606 (316)

Seattle World's Fair schedule of events, June 15-October 21, 1962

open access: yes, 1962
Daily schedule of theatrical performances and other special events held at the World's Fair Opera House, Arena, Playhouse and Stadium from June 15 (roughly two months after the fair's opening day) through October 21, the final day of the fair.The ...
Seattle World's Fair Performing Arts Division
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

標準必要專利FRAND權利金計算──兼論智慧財產法院105年度民專上字第24號判決 FRAND Royalties for Standard Essential Patents and Case Review of Philips v. Gigastorage in Taiwan IP Court

open access: yes交大法學評論, 2019
本文回顧各國法院關於標準必要專利公平、合理、無歧視(FRAND)之權利金計算所作成之司法判決,從比較研究之觀點進行分析及歸納。自美國法院於2013 年作成第一個關於標準必要專利FRAND 權利金計算的判決,各 國法院在FRAND 權利金計算的議題上,已陸續發展出許多值得參考的判決與方法論。本文深入個案進行判決之研究,從中萃取重要之計算方法與論理,描繪出可供依循之FRAND 權利金計算架構,而各國法院採納之具體方 法論以「由上而下法」與「可比較授權法」為主流,有僅採用其中一種方法 ...
莊弘鈺 Hung-Yu Chuang   +2 more
doaj  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

FAIR in practice: minimum metadata schema for bioinformatics analytics by machines. [PDF]

open access: yesJ Biomed Semantics
Wijnbergen D   +9 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

An Economic Model of Fair Use [PDF]

open access: yes
The doctrine of fair use allows limited copying of creative works based on the rationale that copyright holders would consent to such uses if bargaining were possible.
Thomas J. Miceli, Richard P. Adelstein
core  

Community-based health screening and all-cause mortality in rural South Africa: a longitudinal cohort study. [PDF]

open access: yesBMJ Public Health
Magut F   +10 more
europepmc   +1 more source

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