Results 91 to 100 of about 833,606 (316)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Catalog and premium list of the ... annual Natalia District Fair
, 1930 A premium list for the Natalia District Fair in Medina County, listing awards and ...
Natalia District Fair
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Catalogue and premium list of the Grimes County Fair.
, 1935 A pamphlet that list exhibitions and awards for the Grimes County fair.
Grimes County Fair (Tex.); Grimes County Fair Association
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Collaborative Effort Towards a FAIR and OPEN Indo-Pacific Pollen Database (IPPD)
Data Science JournalThe Indo-Pacific Pollen Database (IPPD) is a collection of modern and fossil Australian, Southeast Asian, and Oceanian pollen assemblages collected from Quaternary period depositional contexts. This compilation has been in the making since the late 1980s
Annika V. Herbert +3 more
doaj +1 more source
De Economist, 2002 This paper investigates to what extent fair trade programmes, are indeed ‘fair.’ This is accomplished by comparing fair trade with free trade and protectionist trade regimes on their compliance of the criteria set by the fair trade movement itself. This comparison is made using comparative cost based models and economies of scale models.
Maseland, Robbert, Vaal, Albert de
openaire +5 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Charter and by-laws of the State Fair of Texas.
, 1908 The charter and by-laws of the state fair of Texas.'January, 1908.'' Illustrations on front and back cover. Includes list of ''Officers and directors, 1886-1908.'
State Fair of Texas
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The Kendall County Fair : catalogue and prize list.
, 1935 Content warning: this item contains racist or offensive language.
Kendall County Fair (Boerne, Tex.)
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