Results 91 to 100 of about 1,138,579 (265)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Rules, Regulations and Premium List of The Fifth Annual Fair of the Bell County Fair Association.

open access: yes, 1894
A book of rules and regulations for the fifth annual Bell County ...
Bell County Fair Association (Bell County, Tex.)
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Regulations and premium list of the annual fair of the Bell County Fair Association

open access: yes, 1878
A premium list for the Bell County fair listing awards and prizes.Description based on: 1878.
Bell County Fair Association (Bell County, Tex.)
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

標準必要專利FRAND權利金計算──兼論智慧財產法院105年度民專上字第24號判決 FRAND Royalties for Standard Essential Patents and Case Review of Philips v. Gigastorage in Taiwan IP Court

open access: yes交大法學評論, 2019
本文回顧各國法院關於標準必要專利公平、合理、無歧視(FRAND)之權利金計算所作成之司法判決,從比較研究之觀點進行分析及歸納。自美國法院於2013 年作成第一個關於標準必要專利FRAND 權利金計算的判決,各 國法院在FRAND 權利金計算的議題上,已陸續發展出許多值得參考的判決與方法論。本文深入個案進行判決之研究,從中萃取重要之計算方法與論理,描繪出可供依循之FRAND 權利金計算架構,而各國法院採納之具體方 法論以「由上而下法」與「可比較授權法」為主流,有僅採用其中一種方法 ...
莊弘鈺 Hung-Yu Chuang   +2 more
doaj  

Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research

open access: yesBeilstein Journal of Nanotechnology
Nanosafety assessment, which seeks to evaluate the risks from exposure to nanoscale materials, spans materials synthesis and characterisation, exposure science, toxicology, and computational approaches, resulting in complex experimental workflows and ...
Benjamin Punz   +18 more
doaj   +1 more source

Premium list of the ... annual Eastland County Free Fair.

open access: yes, 1931
Publication listing fair rules and awards with advertisements.Imprint information taken from note on page 11 of issue for 5th (1931). Advertisements interspersed throughout. Includes the fair's rules and regulations and committee members.
Eastland County Free Fair (Tex.)
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Levers for fair work in hospitality in Scotland : Report to the Fair Work Convention [PDF]

open access: yes
This Report presents stakeholder views on fair work challenges and opportunities in the hospitality industry in Scotland. The research underpinning the report is linked to a wider investigation of potential fair work policy levers available to the ...
McQuarrie, Johanna   +3 more
core  

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