Results 141 to 150 of about 1,138,579 (265)
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Ciências Sociais Unisinos, 2016 The article explores the contexts of social construction of markets, focusing on the family farmers’ market at EXPOINTER (Brazil) as research topic. The main goal is to discuss the historical development of this marketplace by using a methodology based ...
Maycon Schubert, Sergio Schneider
doaj
OTHER TITLES: The Kansas State Fair '75 Premium Book, Hutchinson, Sept. 13-21. 1975 Premium Book.
, 1975 The Only Fair in Kansas Owned and Operated by the State for the Benefit of the Entire State. Under the auspices of The Board of State Fair Managers.Program of State Fair events.
Kansas State Fair.
core
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Premium List of the 1979 Kansas State Fair, Hutchinson, Sept. 8-16.
, 1979 Program of State Fair events. Also contains rules, regulations, classes of events, prizes, and other pertinent information regarding the Kansas State Fair, held once a year in Hutchinson Kansas.Index 1979 Kansas State Fair Program Highlights Greetings ...
Kansas State Fair.
core
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
, 1964 THE ONLY FAIR IN KANSAS OWNED AND OPERATED BY THE STATE Under the auspices of The Board of State Fair Managers. Authorized by legislative enactment in 1913 and operated for the benefit of the entire State.Program of State Fair events.
Kansas State Fair.
core
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
OTHER TITLES: The Kansas State Fair 78 Premium Book, Hutchinson, Sept. 9-17. 1978 Premium Book.
, 1978 Program of State Fair events. Also contains rules, regulations, classes of events, prizes, and other pertinent information regarding the Kansas State Fair, held once a year in Hutchinson Kansas.Index 1978 Kansas State Fair Program Highlights Greetings ...
Kansas State Fair.
core