Results 201 to 210 of about 1,138,579 (265)

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Age-specific association between dietary nutrient adequacy and self-rated health in Korean adolescents: a cross-sectional study based on the Korea National Health and Nutrition Examination Survey 2022-2024. [PDF]

Front Nutr
Woo D.
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Advancing FAIR data towards comparable, organized, predictive AI-ready data for community validation. [PDF]

Commun Biol
Wood-Charlson EM, Åkerström WN, Anderson L, Borton MA, Burley SK, Byers N, Chandramouliswaran I, Costes SV, Dehal PS, Doktycz M, Eloe-Fadrosh E, Henry C, Fagnan K, Fiehn O, Halappanavar M, Hurwitz B, Joachimiak MP, Jungbluth S, Koblitz J, Mahmud G, McCue LA, Metz TO, Mouncey N, Mungall CJ, Nelson TM, Skye V, Saravia-Butler AM, Saripalli VR, Tringe SG, Van Den Bossche T, Arkin AP.   +30 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Correction: Scaffold‑based evaluation metrics for fair comparison of molecular generators. [PDF]

J Cheminform
Fil V, Van Den Broek RL, Šicho M, Čmelo I, Agea MI, Jespers W, Van Westen GJP, Svozil D.   +7 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Longitudinal Metabolic Control in Children With Early-Treated Phenylketonuria.

JAMA Netw Open
Wang S, Zhao J, Gong L, Tang Y, Li L, Yang W, Gu L, Kong Y.   +7 more
europepmc   +1 more source

Unveiling the impact of the COVID-19 pandemic on quality indicators of leprosy services in Brazil: an ecological study. [PDF]

BMC Health Serv Res
de Souza CDF, Machado M, Ferreira ACF, de Souza Aragão JA, de Oliveira Fernandes TRM, Matos TS, da Silva TFA, Santos MB, Dos Santos AD, do Carmo RF.   +9 more
europepmc   +1 more source