Results 291 to 300 of about 4,334,434 (396)

Impact of <i>Mycoplasma hominis</i> on Sperm Quality Among Infertile Men: A Systematic Review and Meta-Analysis. [PDF]

Health Sci Rep
Boujemaa S, Suri GS, Kaur G.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Fairness-aware K-means clustering in digital mental health for higher education students: a generalizable framework for equitable clustering. [PDF]

JAMIA Open
Alluri P, Chen Z, Thesen T, Jacobson NC, Marrero WJ.   +4 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

EEG hyperscanning reveals dynamic interbrain network patterns during interactive social decision-making. [PDF]

Commun Biol
Li Y, Si Y, Pang X, Li S, Jiang L, Yi C, Yao D, Li F, Xu P.   +8 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

YOUTH AND DOPING IN SPORTS – A CASE STUDY ON FAIRNESS AND ACCOUNTABILITY

openalex   +1 more source

Lessons learned from implementing FAIRification workflows in diabetes research in Germany. [PDF]

PLOS Digit Health
Inau ET, Dedié A, Anastasova I, Schick R, Fröhlich B, Roden M, Birkenfeld AL, de Angelis MH, Preusse M, Waltemath D, Zeleke AA.   +10 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Beyond the Lens of Lenz: Looking to Protect Fair Use During the Safe Harbor Process Under the DMCA

, 2010
Cattleya Concepcion
openalex   +1 more source