Results 71 to 80 of about 831,592 (316)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2021 <p>According to the <a href="https://www.go-fair.org/fair-principles/">FAIR Principles</a>, research objects should be findable, accessible, interoperable and re-usable.
Sanchez Solis, Barbara, Jaber, Samah
core +1 more source
Iteckne, 2020 Everyday science has had to resort to the construction of large facilities and instruments to carry out experiments that allow obtaining information so that it can be analyzed later.
María F. Robles-Cifuentes +1 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
[Second] annual fair of the Ellis County Fair Association ...
, 1888 Publication describing the Annual fair of Ellis County ...
Ellis County Fair Association (Tex.). Annual Fair.
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Catalogue, Texas Women's Fair, first exclusive women's fair ever held ...
, 1915 A pamphlet filled with advertisements targeted towards homemakers.Full catalog title: Catalogue, Texas Women's Fair, first exclusive women's fair ever held : October 11-16, 1915, Houston ...
Texas Woman's Fair Association
core
Una “feria masiva” de artes plásticas en el ocaso de la última dictadura argentina
Nuevo mundo - Mundos Nuevos, 2016 In 1983, as the last dictatorship in Argentina was in decline, a new art exhibition in the interior of the country was opened: fair known as Art in Córdoba.
Alejandra Soledad González
doaj +1 more source
A short guide to increase FAIRness of atmospheric model data
Meteorologische Zeitschrift, 2020 The generation, processing and analysis of atmospheric model data are expensive, as atmospheric model runs are often computationally intensive and the costs of ‘fast’ disk space are rising.
Anette Ganske +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source