Results 181 to 190 of about 2,278,950 (331)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Performance assessment of ontology matching systems for FAIR data. [PDF]

J Biomed Semantics, 2022
van Damme P, Fernández-Breis JT, Benis N, Miñarro-Gimenez JA, de Keizer NF, Cornet R.   +5 more
europepmc   +1 more source

FAIR Data Digest #23

, 2023
Sven Lieber
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Opportunities for improving data sharing and FAIR data practices to advance global mental health. [PDF]

Glob Ment Health (Camb), 2023
Sadeh Y, Denejkina A, Karyotaki E, Lenferink LIM, Kassam-Adams N.   +4 more
europepmc   +1 more source

ԱՆՁՆԱԿԱՆ ՏՎՅԱԼՆԵՐԻ ԳԱՂՏՆԻՈՒԹՅՈՒՆԸ ԱՐԴԱՐ ԴԱՏԱՔՆՆՈՒԹՅԱՆ ԻՐԱՎՈՒՆՔԻ ՀԱՄԱՏԵՔՍՏՈՒՄ / CONFIDENTIALITY OF PERSONAL DATA IN THE CONTEXT OF THE RIGHT TO A FAIR TRIAL

, 2023
Gnel Gasparyan
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Rethinking the A in FAIR Data: Issues of Data Access and Accessibility in Research. [PDF]

Front Res Metr Anal, 2022
Shanahan H, Bezuidenhout L.
europepmc   +1 more source

Breaking down data sharing barriers and uplifting FAIR for climate data at scale

Clare Richards, K. A. Druken, Romain Beucher, Felicity Chun   +3 more
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source