Results 31 to 40 of about 143,895 (291)

Socjalizująca rola aktywności sportowej dzieci i młodzieży w świetle współczesnej literatury socjologicznej i humanistycznej

open access: yesRozprawy Społeczne, 2020
W artykule podjęto analizę wybranych kilkudziesięciu dzieł współczesnych socjologów i teoretyków sportu i humanistów (publikacje książkowe i artykuły), którzy rozważali rolę sportu w socjalizacji dzieci i młodzieży we współczesnym świecie.
Ryszard Polak, Paweł Tarkowski
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Notebook and Open science : toward more FAIR play [PDF]

open access: yesJournal of Data Mining and Digital Humanities
Notebooks are now commonly used in digital research practices. Despite their increasing ubiquity, the characteristics, roles, and uses associated with notebooks have seldom been studied from a social science perspective.
Mariannig Le Béchec   +3 more
doaj   +1 more source

Financial Fair Play - Implications for Football Club Financial Reporting [PDF]

open access: yes, 2014
Football activities, both on and of the pitch, are often hitting our news. Despite remarkable revenue growth we have seen numerous well known clubs facing an escalation of player costs, unsustainable debt and clubs suffering financial difficulties ...
Morrow, Stephen; id_orcid   +1 more
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

El deporte en una sociedad transhumanista y la necesidad de un fair play tecnológico = Sport in a transhumanist society and the need for a fair technological play

open access: yesMateriales para la Historia del Deporte, 2019
En este trabajo se aborda cómo el deporte tal y como lo conocemos en la actualidad, puede cambiar de manera drástica como consecuencia de las transformaciones tecnológicas. En este sentido he repasado algunas de ellas -ingeniería genética, la robótica en
José Luis Pérez Triviño
doaj  

The constitutive values of fair play

open access: yesActa Universitatis Carolinae Kinanthropologica
Fair play as a phenomenon of sporting life is present even if only in the form of small acts or gestures in most competitions; its absence is present in cases of foul play.
Miloš Bednář
doaj   +1 more source

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