Results 21 to 30 of about 44,442 (246)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Le commerce équitable : un des maillons du développement durable ?

open access: yesDéveloppement Durable et Territoires, 2006
This article questions the notion of an unified Fair trade and shows the various approaches of the actors specialized in this trade exchange. Having summarized the history of the movement, the author underlines the structural indecision of Fair trade ...
Virginie Diaz Pedregal
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Populist Backlash and Trade Agreements in North America: The Prospects for Progressive Trade

open access: yesPolitics and Governance, 2023
Populist rejection of the embedded liberal international order is evident in many Western democracies. This is partly attributable to the architects of this system, who over-promised widespread benefits while ignoring warnings from labour and fair-trade ...
Robert G. Finbow
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

THE WORLD TRADE ORGANIZATION (WTO) FREE TRADE WITHIN FAIR TRADE CHALLENGES

open access: yesMimbar Hukum, 2014
Free trade and fair trade are considered an ambiguous term with relative meanings of identification. Objectively, free and fair trade does not mean completely free and fair, but it means trade under binding rules obeyed by member countries as a ...
M. Ya’kub Aiyub Kadir
doaj   +3 more sources

Practical Implementation of Fair Trade and Social Welfare for Small Producers: Analysis of Mitra Bali Fair Trade Craftsmen

open access: yesJurnal Kajian Bali (Journal of Bali Studies)
Mitra Bali Fair Trade is a business entity that collaborates with craftsmen to implement fair trade practices in the export of Balinese handicraft commodities.
Dewa Ngakan Putu Abhi Mahardika   +1 more
doaj   +1 more source

Exploring the supply chain management of fair trade business: case study of a fair trade craft company in China

open access: yesCogent Business & Management, 2020
For two decades, fair trade has served as an alternative approach of trading that encourages minimal returns, sustainability, and ethics, by offering producers in developing countries better trading conditions and secured rights.
Kaifeng Zhang, Zheng Liu, Ping Wang
doaj   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

FAIR TRADE: A MODEL TO STUDY THE BEHAVIORAL ENTRY DECISION FOR PRODUCERS INTO THE FAIR TRADE MARKET AS WELL AS ITS EFFECT ON HETEROGENEOUS PRODUCERS [PDF]

open access: yesJournal of Economic and Social Development (Varaždin), 2021
In this paper we will try to construct a model to examine the entry decision for producers into Fair Trade market, as well as compare this entry with the normal process, or the heterogenous producers’ model, we will study the discrepancies between the ...
Abdelhamid Nechad, Adam Essakhi
doaj  

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