Results 21 to 30 of about 52,695 (260)
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
The meaning of Fair Trade for wild plants
Where the Fair Trade initiative is applied to wild plants, two contradictory objectives may arise: that of conserving a target plant species (conservation) and that of increasing income from it for collectors (poverty alleviation).
Rie Makita
doaj +1 more source
We consider the age-old problem of allocating items among different agents in a way that is efficient and fair. Two papers, by Dolev et al. and Ghodsi et al., have recently studied this problem in the context of computer systems. Both papers had similar models for agent preferences, but advocated different notions of fairness.
Avital Gutman, Noam Nisan
openaire +4 more sources
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Gaps in expectations of a cotton producer: the case of Rwenzori cotton farmers in Uganda
The plight of the smallholder cotton farmer in the Rwenzori region of western Uganda starts with the unfair terms of hiring land for cultivation. The next hurdle is the loss of ownership of the cotton at the earliest stage of the value chain after ...
Yorokamu K. Abainenamar
doaj +1 more source
Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali +14 more
wiley +1 more source
The ‘burden’ of traceability in gold supply chains
Artisanal and Small-scale Mining (ASM) constitutes 15% (600 tonnes) of global gold production but, as a sector, remains largely veiled to both businesses and consumers in developed Western markets.
David Finlay
doaj +1 more source

