Results 31 to 40 of about 2,059,058 (308)
This paper pursues the purpose of giving insight to researchers and jurists, especially non-Turkish ones, about the progress of the individual application to the Turkish Constitutional Court.
Sedat Erdem Aydın
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
'Despite the fact that we were given an opportunity to address the [Tongan] Parliament and our [Moala and Akau'ola] legal representive was permitted to pose questions relating to the legality of the proceeding, I already felt that we would be found ...
Kalafi Moala
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
In the absence of statutory rules on the matter, Belgian courts traditionally applied a strict exclusionary rule for illegally gathered evidence and its fruits.
Frank Verbruggen, Charlotte Conings
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Can 'Dr Death' receive a fair trial? [PDF]
Identification of a person suspected of a heinous crime before being charged risks prejudicing a fair trial. The identification of rogue former Queensland surgeon Dr jayant Patel is but one recent example.
Burgess, Craig
core
This paper inquires into whether the right to a fair trial can be restricted with regard to alleged terrorists within the framework of the ‘war on terror’.
Kai Ambos, Annika Maleen Poschadel
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

