Results 51 to 60 of about 38,080 (266)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The relationship between the financial crisis and the measurement of fair value in financial statements

open access: yesBuhalterinės Apskaitos Teorija ir Praktika, 2014
Literature suggests that the main goal of fair value evaluation is more reliable and relevant information disclosure to external users. However, in 2007, at the beginning of the global financial crisis, the benefits of fair value, as well as the ...
Birutė Gudonytė   +1 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Fair Value Accounting: The Road to Be Most Travelled [PDF]

open access: yes
Fair value convention has polarized two opposing views – the first, that fair value accounting compounds economic hardship and distortion – and the second, that fair value accounting affords an accurate rendering of the market value of underlying assets ...
Rock Lefebvre   +2 more
core  

Fair value accounting and fair trade: an analysis of the role of international accounting standard no. 41 in social conflict

open access: yes, 2007
The past decade has witnessed a proliferation of accounting pronouncements that indicate that accounting rule-makers around the world are progressively abandoning the traditional historic cost model and actively embracing the fair value paradigm. In this
Elad, C.
core   +1 more source

CHALLENGES INCURRED IN THE AUDITING OF FAIR VALUE MEASUREMENTS [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2016
The purpose of the auditors' work is to establish confidence between the producers and users of accounting information. Thus, auditors help protect the interests of different categories of beneficiaries of accounting information when they make economic ...
Silviu-Virgil Chiriac
doaj  

Consistency, weak fairness, and the Shapley value

open access: yesMathematical Social Sciences, 2020
The Shapley value (Shapley, 1953) has been axiomatically characterized from different points of view. van den Brink (2001) proposes a characterization by means of efficiency, fairness and the null player property. In this paper, we characterize the family of single-valued solutions obtained by relaxing fairness into weak fairness.
Pedro Calleja, Francesc Llerena
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Did Fair-Value Accounting Contribute to the Financial Crisis? [PDF]

open access: yes
The recent financial crisis has led to a major debate about fair-value accounting. Many critics have argued that fair-value accounting, often also called mark-to-market accounting, has significantly contributed to the financial crisis or, at least ...
Christian Leuz, Christian Laux
core  

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