Results 91 to 100 of about 760,410 (305)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
How Does Fair Value Measurement under IAS 39 Affect Disclosure Choices of European Banks? [PDF]
There is a considerable degree of heterogeneity in the way how European banks present their financial instruments in IFRS financial statements. We identify three major presentation formats that are currently applied: a presentation by measurement ...
Bischof, Jannis, Wüstemann, Jens
core
Accounting and the plasticity of valuation [PDF]
, 2015 This chapter explores exemplary moments of dissonance and innovation in accounting valuation. Examining the cases of value-added accounting, brand accounting, fair value accounting and impairment testing, this chapter traces debates and show that ...
Mennicken, Andrea, Power, Michael
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Measurement of non-financial assets at current operational value
Finance, Accounting and Business AnalysisPurpose: In public sector entities, non-financial assets may provide either economic benefits or service potential, depending on their intended use. This distinction influences the selection of an appropriate measurement method.
Mariam Vardiashvili
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The evolution of fair value measurement
Accounting and Business ResearchWhile measurement is a fundamental process to the preparation of financial statements, the conceptual frameworks established by both the International Accounting Standards Board (IASB) and the Financial Accounting Standards Board (FASB) offer limited guidance on selecting an appropriate measurement basis for assets and liabilities.
Fontes, Joana +2 more
openaire +2 more sources
Basic Principles of Hedge Accounting [PDF]
The development of the capital markets increases the key role of the financial manager both in using the new techniques for administrating the risks and in assessing hedge effectiveness.
Bunea-Bontaş, Cristina Aurora
core +1 more source
PERSEPSI AKADEMISI DAN PRAKTISI TERHADAP PENERAPAN NILAI WAJAR DI INDONESIA [PDF]
, 2015 This study aimed to analyze the perception of academic and practitioner on the implementing of fair value in Indonesia. The implementing of fair value in Indonesia is still a new thing, because many companies are still using the historical cost.
HARTO, Puji, PUTRA, Tias Nugraha
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source