Results 171 to 180 of about 760,410 (305)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Accurate quantification of steps from multiple smartphone positions. [PDF]

Sci Rep
Ena A, Mazzà C, Rodríguez-Romero A, Woelfle T, Mueller J, Granziera C, Kappos L, Bartholomé E, Bernasconi C, Belachew S, Reyes Ó.   +10 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

The Diagnostic Utility of Lateral Thumb Radiographs in Detecting Thumb Carpometacarpal Arthritis. [PDF]

J Hand Surg Glob Online
Gao B, Cogsil T, Dearden M, Wang N, Reddy K, Lee SK.   +5 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Quantitative 3D assessment of marginal impaction volume in posterior wall acetabular fractures: a pilot study. [PDF]

J Orthop Surg Res
Topsakal FE, Özdemir E, Altay N, Ağ FB, Şahbat Y, Demirel E.   +5 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Advanced signal-processing framework for remote photoplethysmography-based heart rate measurement: Integrating adaptive Kalman filtering with discrete wavelet transformation. [PDF]

PLoS One
Debnath U, Kim S.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Associations of combined hearing loss and depression with cognitive impairment among older adults: a sex difference analysis based on evidence from CHARLS. [PDF]

BMC Public Health
Li P, Liu Q, Ma L, Huang J, Shi J, Yang D, Su Y, Xie H.   +7 more
europepmc   +1 more source