Results 191 to 200 of about 251,092 (316)

ShapeField-lung: continuous shape embedding for early lung cancer detection via pulmonary nodule segmentation. [PDF]

NPJ Digit Med
Gu X, Zhu Y, Li C, Xu X, Jin K, Xu L.
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

MoleProLink-RL: geometric transport for domain-policy reinforcement learning in drug-target interaction prediction. [PDF]

NPJ Digit Med
Xu D, Wang B, Zhu D, Zheng C, Wu H, Wang R, Sun J, Xie M, Li X, Wu L, Zhang C.   +10 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Letter to the Editor Regarding "Predictive Value of Neutrophil-to-Lymphocyte Ratio for Cerebral Infarction in Obstructive Sleep Apnea: A Nomogram-Based Analysis" [Response to Letter]. [PDF]

Nat Sci Sleep
Hou Z, Chen C, Liu H, Wang Y, Li Z.
europepmc   +1 more source

FAITHFUL REPRESENTATION AND FIRM PERFORMANCE: INSIGHTS FROM AGENCY AND SIGNALING THEORY

Imam Nurcahyo Fambudi, Sri Opti, Lolla, Mishelei Loen, Khoirina Farina   +4 more
openalex   +1 more source

The Magnus representation of the Torelli group $\mathcal {I}_{g,1}$ is not faithful for $g \geq 2$ [PDF]

, 2001
Masaaki Suzuki
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Plug-and-play computational method for advancing natural and biomedical image representation. [PDF]

Patterns (N Y)
Gong H, Han T, Li G.
europepmc   +1 more source

Attacks on the Faithfulness of the Burau Representation of the Braid Group $B_4$

, 2016
Mohammad Y. Chreif, Mohammad N. Abdulrahim   +1 more
openalex   +2 more sources