Results 241 to 250 of about 251,092 (316)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Bridging clinical knowledge and AI: an interpretable transformer framework for ECG diagnosis. [PDF]

NPJ Digit Med
Yisimitila T, Wang C, Hou M, Maimaitiniyazi M, Aili Z, Liu T, Tan H, Chellamani N, Shanmuganathan M, Liu M, Nijiati M.   +10 more
europepmc   +1 more source

A Faithful Representation of Temperley-Lieb Algebras in Matrices

, 2002
Kosta Došen, Z. Kovijanic, Zoran Petrić   +2 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Should I stay or should I go? Causes and consequences of intraspecific variation in site fidelity. [PDF]

Mov Ecol
Huggler KS, Smiley RA, Wagler BL, Courtemanch AB, Gregory Z, Monteith KL, Shipley LA, Stewart C, Wik P, Cassirer EF, Long RA.   +10 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Benchmarking Interpretability in Healthcare Using Pattern Discovery and Disentanglement. [PDF]

Bioengineering (Basel)
Zhou PY, Takeuchi A, Martinez-Lopez F, Ehghaghi M, Wong AKC, Lee EA.   +5 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

ADBM: Adversarial Diffusion Bridge Model for Denoising of 3D Point Cloud Data. [PDF]

Sensors (Basel)
Nam C, Lee SJ.
europepmc   +1 more source

On faithful representations of free groups

Kodai Mathematical Journal, 1949
openaire   +2 more sources