Results 61 to 70 of about 141,811 (278)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

{The faithful triangular representations of Kaloujnine $p$-groups over a $p$-element field

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2011
The faithful triangular representations of finite Kaloujnine$p$-groups is studied. Images of generators of those groups aredescribed. Infinite-dimensional representation of the direct limitof Kaloujnine $p$-groups is regarded.
Y. G. Leonov
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

When is a container a comonad? [PDF]

open access: yesLogical Methods in Computer Science, 2014
Abbott, Altenkirch, Ghani and others have taught us that many parameterized datatypes (set functors) can be usefully analyzed via container representations in terms of a set of shapes and a set of positions in each shape.
Danel Ahman   +2 more
doaj   +1 more source

FINITE METACYCLIC GROUPS WITH FAITHFUL IRREDUCIBLE REPRESENTATIONS [PDF]

open access: yesBulletin of the Korean Mathematical Society, 2003
Let the finite group \(G\) possess a normal cyclic subgroup \(K\) such that \(G/K\) is cyclic. In that case, the subgroup \(A=C_G(K)\) is Abelian and normal in \(G\). Then \(G\) has a faithful irreducible representation over a field \(\mathbb{F}\) if and only if it satisfies one of the following conditions: (a) The characteristic of \(\mathbb{F}\) does
openaire   +2 more sources

Faithful Representations of Graph Algebras via Branching Systems [PDF]

open access: yesCanadian Mathematical Bulletin, 2016
Abstract We continue to investigate branching systems of directed graphs and their connections with graph algebras. We give a suõcient condition under which the representation induced from a branching systemof a directed graph is faithful and construct a large class of branching systems that satisfy this condition.
Gonçalves, Daniel   +2 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Embedding and publishing interactive, 3-dimensional, scientific figures in Portable Document Format (PDF) files. [PDF]

open access: yesPLoS ONE, 2013
With the latest release of the S2PLOT graphics library, embedding interactive, 3-dimensional (3-d) scientific figures in Adobe Portable Document Format (PDF) files is simple, and can be accomplished without commercial software. In this paper, we motivate
David G Barnes   +5 more
doaj   +1 more source

Minimal dimension of faithful representations for p-groups [PDF]

open access: yesJournal of Group Theory, 2016
Abstract For a group G, we denote by m faithful ⁢
Bardestani, Mohammad   +2 more
openaire   +3 more sources

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