Results 81 to 90 of about 141,811 (278)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

THE LEFT REGULAR REPRESENTATION OF A COMMUTATIVE SEPARATIVE SEMIGROUP [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 1992
In this paper, a commutative semigroup will be written as a disjoint union of its cancellative subsemigroups. Based on this fact we will define the left regular representation of a commutative separative semigroup and show that this representation is ...
doaj  

On AdS4 superspace and supergravity

open access: yesJournal of High Energy Physics
In the N = 1 superspace, AdS4 supersymmetry is realized as the non-linear super coordinate transformations. The fermionic coordinates form a faithful non-linear representation of supersymmetry on their own.
Chen-Xu Han, Zhao-Long Wang, Yi Yan
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

On some interpretation of linear frames in projective differential geometry

open access: yesДифференциальная геометрия многообразий фигур, 2018
The centroprojective group, i. e. the stabilizer G of a fixed point A in the group GP(n) of projective transformations of n-dimensional projective space Pn (n > 1) is considered in the paper. Two faithful representations of the linear quotient group of G
A. Kuleshov
doaj  

The Soundscape of Pasolinis The Gospel According to St. Matthew

open access: yesJournal for Religion, Film and Media, 2019
Il Vangelo secondo Matteo (The Gospel According to St. Matthew, IT/FR 1964), by the Italian film director Pier Paolo Pasolini, is one of the most interesting and widely acclaimed film representations of the life of Jesus.
Nicola Martellozzo
doaj   +1 more source

No Country for Old X-Men: The Aging Hero in No Country for Old Men and Logan

open access: yes[sic], 2020
The American Western is imbued with a particular elasticity, which allowed it to stay relevant for decades. One of the recent developments in the genre seems to be its focus on the aging frontiersman – a hero past its prime.
Ljubica Matek, Zvonimir Prtenjača
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Constructing faithful matrix representations of Lie algebras

open access: yesProceedings of the 1997 international symposium on Symbolic and algebraic computation - ISSAC '97, 1997
By Ados theorem every nite dimensional Lie algebra over a eld of characteristic zero has a faithful nite dimensional representation We consider the algorithmic problem of constructing such a representation for Lie algebras given by a multiplication table An eective version of Ados theorem is proved.
openaire   +3 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

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