Results 51 to 60 of about 110,130 (282)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
"Liar, Liar Pants on Fire": A New Benchmark Dataset for Fake News Detection
, 2017 Automatic fake news detection is a challenging problem in deception detection, and it has tremendous real-world political and social impacts. However, statistical approaches to combating fake news has been dramatically limited by the lack of labeled ...
Wang, William Yang
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Detecion of Opinion Spam in Online Reviews [PDF]
, 2015 The rise of Internet has led to consumers constantly and increasingly review and research products and services online. Consequently, websites that garner such reviews become primary targets for opinion Spam, which essentially means to sway public ...
Rungta, Shaswat
core
Fake Product Review Monitoring System
International Journal for Research in Applied Science and Engineering Technology, 2022 Abstract: In the current scenario, the data on the web is growing to a larger extent. Social Media is generating a large amount of data such as reviews, comments and customer’s opinions on a daily basis. This huge amount of user generated data is worthless unless some miningt e c h n i q u e s are applied to it. Nowadays, there are several people using
Deekshitha K UG, Deepa R
openaire +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Fake Review Detection From a Product Review Using Modified Method of Iterative Computation Framework
MATEC Web of Conferences, 2016 The rapid growth of the Internet influenced many of our daily activities. One of the very rapid growth area is ecommerce. Generally e-commerce provide facility for customers to write reviews related with its service. The existence of these reviews can be
Wahyuni Eka Dyar, Djunaidy Arif
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source