Results 61 to 70 of about 110,130 (282)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Automatic detection of fake reviews at marketplaces using expert-based features and consumers’ reactions

Цифровая социология
The article presents the results of a practical study of the features of fake reviews that are described by marketers and other experts. Due to the abundance of fake reviews on marketplaces, consumer trust falls not only in the seller or platform, but in
A. N. Borodulina, E. V. Mikhalkova
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Spotting Suspicious Link Behavior with fBox: An Adversarial Perspective

, 2014
How can we detect suspicious users in large online networks? Online popularity of a user or product (via follows, page-likes, etc.) can be monetized on the premise of higher ad click-through rates or increased sales.
Beutel, Alex, Faloutsos, Christos, Gallagher, Brian, Shah, Neil   +3 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Detecting Fake Reviews Using Aspect-Based Sentiment Analysis and Graph Convolutional Networks

Applied Sciences
Online reviews significantly influence consumer behavior and business reputations. Detecting fake reviews is important for maintaining trust and integrity in these platforms.
Prathana Phukon, Petros Potikas, Katerina Potika   +2 more
doaj   +1 more source

Seminar Users in the Arabic Twitter Sphere

, 2017
We introduce the notion of "seminar users", who are social media users engaged in propaganda in support of a political entity. We develop a framework that can identify such users with 84.4% precision and 76.1% recall.
A Almaatouq, A Binns, A Zubiaga, AM Kaplan, C Castillo, C Hardaker, C Ruiz, C Wells, D Liu, E Ferrara, E Ferrara, EE Buckels, F Sebastiani, FJ Ortega, G Sarna, KK Cole, KS Adewole, M Hardalov, M McCord, MJ Moore, P Galán-García, P Shachaf, PT Slee, S Cresci, S Stieglitz, S Thacker, S Virkar, S Waisbord, W Li, Y Song, Z Bu   +30 more
core   +1 more source

Spotting fake reviewer groups in consumer reviews [PDF]

Proceedings of the 21st international conference on World Wide Web, 2012
Opinionated social media such as product reviews are now widely used by individuals and organizations for their decision making. However, due to the reason of profit or fame, people try to game the system by opinion spamming (e.g., writing fake reviews) to promote or demote some target products.
Arjun Mukherjee, Bing Liu, Natalie Glance   +2 more
openaire   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Truth, Lies, and Copyright [PDF]

, 2019
Fake news may be trending right now, but fake news is not the only source of fake facts that we consume. We encounter fake facts every day in the historical or biographical books we read, the movies we watch, the maps we study, the tele-phone directories
Smith, Cathay Y. N.
core   +3 more sources