Results 221 to 230 of about 131,711 (285)

Active pH Modulation by Proton Channel‐Peptide Nucleic Acid Complex for Effective siRNA Endosomal Escape

Small, EarlyView.
A bioinspired siRNA nanocarrier is engineered by integrating an influenza A M2 proton channel with siRNA through a peptide nucleic acid linker on liposome surfaces. Active proton transport amplifies osmotic stress within endosomes, triggering membrane rupture and cytosolic release.
Seongmin Ga, Nam Hyeong Kim, Si Yeon Ryu, Kyeonghyun Kim, Eun Sung Kang, Hayeon Bae, Seungmin Ryu, Suhyeon Kim, Yeontae Jang, Bok‐Soo Lee, Jiyoung Nam, Minah Suh, Jaecheol Lee, Seung‐gu Kang, Jaekyung Hyun, Huong T. Kratochvil, Yong Ho Kim   +16 more
wiley   +1 more source

The Falcon

Animal Studies Journal
openaire   +2 more sources

AB jailbreaking - a novel hybrid framework for exploitation of adversarial vulnerabilities in LLMs. [PDF]

Sci Rep
Ahmad A, Naseer M, Qamar U, Alfuraidan M.   +3 more
europepmc   +1 more source

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

Small, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung, Gargi Yogesh Digholkar, Ryan M. Pearson   +2 more
wiley   +1 more source

Bridging methodological gaps in avian cytogenetics: comprehensive and optimized protocols for chromosomal preparation in birds. [PDF]

Chromosome Res
de Bello Cioffi M, Toma GA, Setti PG, Vidal JAD, Mota-Souza G, Altmanová M, de Oliveira EHC, Kretschmer R.   +7 more
europepmc   +1 more source

Photo‐Activated Merging Cascades in Droplet Swarms Upon Synergistic Solvation of Surfactants

Small, EarlyView.
UV activates the motility of UV‐responsive droplets through a decylammonium/carbamate crystalline layer at the air/water interface. Upon merging with immobilized C12E3 surfactant droplets in the layer, hybrid droplets form which dissolve the layer due to synergistic solvation. In large droplet fields, this non‐linear behavior drives cascading events of
Priyanshu Singh, Roël M. Vreuls, Gerco W. A. Meeussen, Peter A. Korevaar   +3 more
wiley   +1 more source

FALCON2: compression-based metagenomic classification of ancient viruses. [PDF]

Bioinformatics
Marques LL, Pinho AJ, Pratas D.
europepmc   +1 more source

Predictive Amphiphile Design Enables Control of Self‐Assembled Nanoparticle‐Cell Membrane Interactions

Small, EarlyView.
The interactions of self‐assembled nanocarriers with cell membranes are programmable through amphiphile design. We identify how head and tail chemistry govern distinct interaction mechanisms and introduce ΔGtransfer, a unified thermodynamic descriptor that predicts nanoparticle behaviour from simple molecular simulations.
Mahsa Nami, Tiffany Guitton‐Spassky, Farhad Sharif, Natalie Hanheiser, Riensqia Saudale, Jannik Gabriel, Aarti, Alireza Mirzaalipour, MohammadJavad Hafezi, Boris Schade, Abhishek Kumar Singh, Rainer Haag, Roland R. Netz, Hesam Makki   +13 more
wiley   +1 more source

Environmental drivers of Odonate assemblages across biogeographic provinces in the Mexican Transition Zone. [PDF]

Biodivers Data J
Silva-Hurtado JD, Martínez-Falcón AP, Goyenechea I, López-Mendoza S, Octavio-Aguilar P.   +4 more
europepmc   +1 more source

Tailoring MXene Flake Morphology via Aerosol Jet Printing for Biological and Strain Sensor Applications

Small, EarlyView.
Aerosol Jet Printing (AJP), coupled with a novel in situ monitoring method, enabled the controlled fabrication of aligned and crumpled Ti3C2Tx MXenes for diverse applications. Demonstrated across multiple 2D materials, this scalable strategy stablishes flake morphology as a controllable design parameter for engineering application‐specific material ...
Javier Gutierrez‐Gonzalez, Dahnan Spurling, Cian O'Connor, Eoin Caffrey, Tara McGuire, Jack Maughan, Tian Carey, Jose Munuera, Ilias M. Oikonomou, Julian Carolan, Luke Doolan, Ian Woods, Giulio Brunetti, Maeve A. Caldwell, Adrian Dervan, Richard G. Hobbs, Jonathan N. Coleman, Valeria Nicolosi, Fergal J. O'Brien   +18 more
wiley   +1 more source