Results 131 to 140 of about 44,802 (277)

NUAK2 Inhibition Enhances Macromolecular Drug Delivery in a 3D Fibrotic Model of the Pancreatic Tumor Microenvironment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura   +14 more
wiley   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

open access: yesAdvanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer   +5 more
wiley   +1 more source

Construction and monetary policy: a view from the sidelines [PDF]

open access: yes
This Commentary is adapted from Ms. Pianalto's remarks at the annual forecast dinner of the Home Builders' Association of Greater Akron, January 27, 1999.Economic conditions - United States ; Monetary ...
Sandra Pianalto
core  

Compositional Characterization, Quality Parameters, and Physicochemical and Bioactive Properties of Pequi (Caryocar brasiliense) Oils From Xingu and Cerrado in Mato Grosso, Brazil

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
Cerrado oil is richer in MUFA and antioxidant compounds, while Xingu oil shows higher SFA and enhanced oxidative stability, reinforcing the potential of pequi oil as a sustainable bioactive ingredient. ABSTRACT Pequi (Caryocar brasiliense) is a native fruit widely distributed in Brazilian biomes, specially in Cerrado, known for its high oil yield and ...
Dhayna O. Sobral   +8 more
wiley   +1 more source

The Cowl - v.27 -n.18 - Oct 09, 1974 [PDF]

open access: yes, 1974
The Cowl - student newspaper of Providence College. Volume 27, Number 18 - October 9, 1974. 10 pages. Note: The volume number printed on the banner page of this issue (XXVII) duplicates the volume number for 1964-65 academic ...

core   +1 more source

Impact of Pumpkin and Carrot Flours on the Oxidative and Rheological Properties: Properties of Low‐Fat Cold‐Pressed Oil Mayonnaise

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
Partial substitution of sunflower oil with cold‐pressed oils (0‐20%) improves the bioactive composition, oxidative stability, and overall quality of mayonnaise while preserving emulsion stability. ABSTRACT This study investigates the effects of xanthan gum, carrot flour, and pumpkin flour on the physicochemical, rheological, and bioactive properties of
S. Gülen   +2 more
wiley   +1 more source

Spartan Daily, November 14, 2018 [PDF]

open access: yes, 2018
Volume 151, Issue 36https://scholarworks.sjsu.edu/spartan_daily_2018/1078/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +2 more sources

Preparation of MOEAMCl and MAAm Based Hydrogels and Effective Use in Anionic Dye Adsorption

open access: yesJournal of Applied Polymer Science, Volume 142, Issue 16, April 20, 2025.
ABSTRACT In this study, hydrogels based on [2‐(Methacryloyloxy)ethyl]trimethylammonium chloride (MOEAMCl) and methacrylamide (MAAm) were synthesized for the removal of anionic dyes from aqueous solutions. Following detailed characterization, the use of hydrogels for methyl orange (MO) adsorption was investigated.
Hilal Nur Duykop Demir   +3 more
wiley   +1 more source

Role of soft tissue and bone interactions in the developmental integration and modularity of the skull in neural crest‐specific gap junction alpha‐1 knockout mice

open access: yesThe Anatomical Record, EarlyView.
Abstract The vertebrate skull is composed of bones derived from neural crest cells and mesoderm. The evolutionary capacity of the skull has been linked, in part, to the emergence of neural crest cells; however, this increased capacity for evolutionary change requires that variation within neural crest‐ and mesoderm‐derived bones remains partly ...
Alyssa C. Moore   +5 more
wiley   +1 more source

Morpho‐functional analyses of the jaw apparatus in the Blue‐and‐yellow Macaw (Ara ararauna, Psittaciformes, Aves): Adaptations to feeding behavior

open access: yesThe Anatomical Record, EarlyView.
Abstract Macaws are renowned for processing dry, mechanically resistant fruits, yet the species‐level anatomical and functional correlates of this performance remain incompletely resolved. We examined the feeding apparatus of the Blue‐and‐yellow Macaw (Ara ararauna) using an integrated approach that combines osteology, myology, and bite‐force estimates
Sérgio R. Posso   +2 more
wiley   +1 more source

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