Results 91 to 100 of about 1,144,100 (291)

Automatic Detection of Falls and Fainting [PDF]

, 2013
Los entornos sanitarios siempre se han considerado un escenario importante en el que aplicar nuevas tecnologías para mejorar las condiciones de los residentes y los empleados, resolver problemas y facilitar la realización de tareas. De esta forma, el uso de sensores basados en la interacción con el movimiento del usuario permite resolver situaciones ...
Garrido,Juan, Penichet,Victor, Lozano,María, Valls,José A. F.   +3 more
openaire   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

A comparison between heuristic and machine learning techniques in fall detection using Kinect v2 [PDF]

, 2016
In this paper, two algorithms were tested on 11 healthy adults: one based on heuristic and another one on video tagging machine learning methods for automatic fall detection; both utilizing Microsoft Kinect v2.
Amini, A, Banitsas, K, Cosmas, J
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Risk management in solitary agricultural work: new technologies for handling emergency and falls from great heights (SHADE) [PDF]

, 2015
Solitary work and agricultural activities are the scenarios of a large number of severe injuries and deaths, also because first aid may be difficult to achieve in isolated locations.
Boscariol, Paolo, Dell\u2019Antonia, D., Fanzutto, A., Gasparetto, Alessandro, Moro, L., Zucchiatti, N.   +5 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Sensitivity plots for WIMP direct detection using the annual modulation signature [PDF]

, 1999
Annual modulation due to the Earth's motion around the Sun is a well known signature of the expected WIMP signal induced in a solid state underground detector.
A. Morales, A. Ortiz de Solórzano, A. Peruzzi, Abriola, Baudis, Belli, Bernabei, Bernabei, Bernabei, Brhlik, D. González, Drukier, E. Garcı́a, Freese, Garcia, Hasenbalg, I.G. Irastorza, J. Morales, J. Puimedón, J.A. Villar, Jungman, M.L. Sarsa, Ramachers, S. Cebrián, S. Scopel, Sarsa   +25 more
core   +2 more sources

Exploring factors affecting the acceptance of fall detection technology among older adults and their families: a content analysis

BMC Geriatrics
Background This study conducted in-depth interviews to explore the factors that influence the adoption of fall detection technology among older adults and their families, providing a valuable evaluation framework for healthcare providers in the field of ...
Hsin-Hsiung Huang, Ming-Hao Chang, Peng-Ting Chen, Chih-Lung Lin, Pi-Shan Sung, Chien-Hsu Chen, Sheng-Yu Fan   +6 more
doaj   +1 more source