Results 81 to 90 of about 1,144,100 (291)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
TagFall: Towards Unobstructive Fine-Grained Fall Detection based on UHF Passive RFID Tags [PDF]
EAI Endorsed Transactions on Internet of Things, 2015 Falls are among the leading causes of hospitalization for the elderly and illness individuals. Considering that the elderly often live alone and receive only irregular visits, it is essential to develop such a system that can effectively detect a fall or
Wenjie Ruan +5 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Multisensor Data Fusion for Human Activities Classification and Fall Detection [PDF]
, 2017 Significant research exists on the use of wearable sensors in the context of assisted living for activities recognition and fall detection, whereas radar sensors have been studied only recently in this domain.
Cippitelli, Enea +8 more
core +1 more source
Abstract As the global population ages, the incidence of falls among the older adults increases, necessitating advancements in fall detection and prevention technologies. This chapter provides a comprehensive overview of the current state of these technologies in the context of Active Assisted Living (AAL).
Jennifer Lumetzberger +2 more
openaire +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Detecting Irregular Patterns in IoT Streaming Data for Fall Detection
, 2018 Detecting patterns in real time streaming data has been an interesting and challenging data analytics problem. With the proliferation of a variety of sensor devices, real-time analytics of data from the Internet of Things (IoT) to learn regular and ...
Isah, Haruna +3 more
core +1 more source
An information-theoretic approach to the gravitational-wave burst detection problem [PDF]
, 2017 The observational era of gravitational-wave astronomy began in the Fall of 2015 with the detection of GW150914. One potential type of detectable gravitational wave is short-duration gravitational-wave bursts, whose waveforms can be difficult to predict ...
Essick, Reed +4 more
core +4 more sources
Robust Self-Adaptation Fall-Detection System Based on Camera Height
Sensors, 2019 Vision-based fall-detection methods have been previously studied but many have limitations in terms of practicality. Due to differences in rooms, users do not set the camera or sensors at the same height.
Xiangbo Kong +5 more
doaj +1 more source