Results 31 to 40 of about 1,030,403 (250)

Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma

Nature Communications, 2019
The cell-of-origin of high grade serous ovarian carcinoma (HGSOC) remains controversial, with fallopian tube epithelium (FTE) and ovarian surface epithelium (OSE) both considered candidates.
Shuang Zhang, Igor Dolgalev, Tao Zhang, H. Ran, D. Levine, B. Neel   +5 more
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Fallopian tube initiation of high grade serous ovarian cancer and ovarian metastasis: Mechanisms and therapeutic implications.

Cancer Letters, 2020
Ovarian cancer is the most lethal gynecologic malignancy and the fifth leading cause of cancer-related death in women. Although outcomes have improved in recent years, there remains an unmet clinical need to understand the early pathogenesis of ovarian ...
Tova M Bergsten, J. Burdette, M. Dean
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Exposure of human fallopian tube epithelium to elevated testosterone results in alteration of cilia gene expression and beating.

Human Reproduction, 2020
STUDY QUESTION How does exposure to a testosterone rich environment affect the function and gene expression of human fallopian tube epithelium (hFTE)?
T. Jackson-Bey, J. Colina, Brett C Isenberg, J. Coppeta, M. Urbanek, J. J. Kim, Teresa K. Woodruff, Joanna E Burdette, A. Russo   +8 more
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The repertoire of serous ovarian cancer non-genetic heterogeneity revealed by single-cell sequencing of normal fallopian tube epithelial cells

bioRxiv, 2019
The inter-differentiation between cell states promotes cancer cell survival under stress and fosters non-genetic heterogeneity (NGH). NGH is, therefore, a surrogate of tumor resilience but its quantification is confounded by genetic heterogeneity.
Zhiyuan Hu, Mara Artibani, Abdulkhaliq Alsaadi, N. Wietek, M. Morotti, Laura Santana Gonzalez, Salma El-Sahhar, Mohammad Karaminejadranjbar, Garry Mallett, Tingyan Shi, K. Masuda, Yiyan Zheng, K. Chong, S. Damato, S. Dhar, R. Campanile, H. S. Majd, V. Cerundolo, T. Sauka-Spengler, C. Yau, A. Ahmed   +20 more
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Integrative Transcriptome Analyses of the Human Fallopian Tube: Fimbria and Ampulla—Site of Origin of Serous Carcinoma of the Ovary

Cancers, 2020
Epithelial ovarian cancer represents a group of heterogeneous diseases with high grade serous cancer (HGSC) representing the most common histotype. Molecular profiles of precancerous lesions found in the fallopian tube have implicated this tissue as the ...
R. Sowamber, O. Nelson, Leah Dodds, Victoria DeCastro, I. Paudel, Anca Milea, M. Considine, L. Cope, A. Pinto, M. Schlumbrecht, B. Slomovitz, P. Shaw, S. George   +12 more
semanticscholar   +1 more source

Radial compliance of porcine Fallopian tubes ex vivo – perspectives for the development of a gynecological microstent

Current Directions in Biomedical Engineering, 2023
Fallopian tube occlusions represent one of the most common causes of female sterility. As an innovative treatment approach for affected persons, we previously presented the concept of a novel polymeric, self-expanding, and bioresorbable microstent.
Siewert Stefan, Dierke Ariane, Stahnke Thomas, Großmann Swen, Brandt-Wunderlich Christoph, Supp Laura, Rosam Paula, Stiehm Michael, Bock Andrea, Zygmunt Marek, Schmitz Klaus-Peter   +10 more
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Microstent for minimally invasive treatment of Fallopian tube occlusions – porcine implantation ex vivo

Current Directions in Biomedical Engineering, 2022
Involuntary female infertility represents a sensitive issue, which is frequently caused by an impaired patency of the Fallopian tube. Current treatment options, such as in vitro fertilisation (IVF) or tubal reconstruction, are related to high costs or ...
Dierke Ariane, Klußmann-Fricke Bastian-Jesper, Rosam Paula, Brandt-Wunderlich Christoph, Knorre Luise, Stiehm Michael, Bock Andrea, Grabow Niels, Wree Andreas, Zygmunt Marek, Schmitz Klaus-Peter, Siewert Stefan   +11 more
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Tuberculous Salpingitis: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2013
Tuberculosis (TB) of the genital tract commonly occurs secondary to a primary lesion. The mode of spread is via the lymphatics, the haematogenous route or less commonly by a peritoneal spread. The fallopian tubes are the first targets, followed by the
Annie Rajaratnam, Prema D’Cunha, Zevita Furtado, Hilda Fernandes   +3 more
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Case Report: Frontoparietal Metastasis From a Primary Fallopian Tube Carcinoma

Frontiers in Surgery, 2021
Background: Metastatic brain tumors typically arise from primary malignancies of the lung, kidney, breast, skin, and colorectum. Brain metastases originating from malignancies of the female genital tract are extremely rare. We present a case of fallopian
Anthony I. Jang, Joshua D. Bernstock, David J. Segar, Marcello Distasio, Ursula Matulonis, Wenya Linda Bi   +5 more
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Combined assembloid modeling and 3D whole-organ mapping captures the microanatomy and function of the human fallopian tube

Science Advances
The fallopian tubes play key roles in processes from pregnancy to ovarian cancer where three-dimensional (3D) cellular and extracellular interactions are important to their pathophysiology.
Ashleigh J. Crawford, André Forjaz, J. Bons, Isha Bhorkar, Triya Roy, David Schell, Vasco Queiroga, Kehan A. Ren, Donald Kramer, Wilson Huang, Gabriella C. Russo, Meng-Horng Lee, Pei-Hsun Wu, I. Shih, Tian-Li Wang, M. Atkinson, B. Schilling, Ashley L. Kiemen, Denis Wirtz   +18 more
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