Results 61 to 70 of about 2,482,501 (258)

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Low‐Grade Serous Carcinoma in Association With Endosalpingiosis in a Cervical Lymph Node: A Case Report and Literature Review

Diagnostic Cytopathology, EarlyView.
ABSTRACT Endosalpingiosis is a benign Müllerian inclusion that rarely involves supradiaphragmatic lymph nodes. Malignant transformation in the setting of nodal endosalpingiosis is exceptional. We report a case of low‐grade serous carcinoma arising in a cervical lymph node in the setting of endosalpingiosis in a 41‐year‐old woman presenting with Horner ...
Nyein Nyein Htun, Nour Sneige
wiley   +1 more source

High‐grade serous peritoneal cancer follows a high stromal response signature and shows worse outcome than ovarian cancer

Molecular Oncology, 2021
In the era of personalized medicine, where transition from organ‐based to individualized genetic diagnosis takes place, the tailoring of treatment in cancer becomes increasingly important.
Francis Jacob, Rosa Lina Marchetti, André B. Kind, Kenneth Russell, Andreas Schoetzau, Viola A. Heinzelmann‐Schwarz   +5 more
doaj   +1 more source

Leiomyoma and leiomyoma cellulare of the fallopian tube: review of the literature and case reports

, 2016
Introduction: Leiomyoma of the fallopian tube is extremely rare, and its version – leiomyoma cellulare (LC) of the fallopian tube is absolutely unique.
Dobrosława L. Sikora-Szczęśniak
core   +1 more source

Cross‐Regulation Between DNA Methylation and Circadian Clock Reprogramming in Ovarian Cancer: Mechanistic Insights, Biomarker Potential, and Therapeutic Implications

International Journal of Cancer, EarlyView.
ABSTRACT Early diagnosis remains challenging, recurrence rates remain high, and platinum resistance frequently develops in ovarian cancer (OC), collectively representing major barriers to long‐term patient survival. DNA methylation (DNAm), as a relatively stable yet dynamically modifiable epigenetic signature, can capture alterations in tumor states ...
Min Xing, Chang Zhou, Yi Tang, Shuhui Xu, Shasha Zhou, Weiai Liu, Huiping Liu   +6 more
wiley   +1 more source

A high-resolution spatial map of cilia-associated proteins in the human fallopian tube

Nature Communications
Molecular alterations in the fallopian tubes play a pivotal role in the development of cancer and reproductive disorders, yet their molecular landscape at the protein level remains poorly defined.
Feria Hikmet, Andreas Digre, Jan Niklas Hansen, Samantha B. Schon, Emma Lundberg, Matts Olovsson, Mathias Uhlén, Loren Méar, Cecilia Lindskog   +8 more
doaj   +1 more source

Evaluation of women’s aging influence on sperm passage inside the fallopian tube using 3D dynamic mechanical modeling

Frontiers in Bioengineering and Biotechnology
The fallopian tubes play an important role in human fertility by facilitating the spermatozoa passage to the oocyte as well as later actively facilitating the fertilized oocyte transportation to the uterus cavity.
Mayssam Nassir, Mattan Levi, Amir Wiser, Natan T. Shaked   +3 more
doaj   +1 more source

Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases

Stem Cells International, 2019
Female infertility impacts the quality of life and well-being of affected individuals and couples. Female reproductive diseases, such as primary ovarian insufficiency, polycystic ovary syndrome, endometriosis, fallopian tube obstruction, and Asherman ...
Yun-xia Zhao, Shao-rong Chen, Ping-ping Su, Feng-huang Huang, Yan-chuan Shi, Qi-yang Shi, Shu Lin   +6 more
doaj   +1 more source

Spontaneous hemoperitoneum in a 29‐week pregnancy with a history of endometriosis: A case report and review of the literature

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 31-37, April 2025.
Abstract Spontaneous hemoperitoneum in pregnancy (SHIP) is defined as sudden, nontraumatic intraperitoneal bleeding that occurs during pregnancy or up to 42 days postpartum. The incidence ranges between 4 and 4.9 per 100 000 births. Although seen rarely, it is associated with perinatal morbidity and mortality due to maternal hemodynamic instability ...
Shamsi Mehdiyev, Fatma Basak Tanoglu, Esma Demir Altuncu, Engin Oral   +3 more
wiley   +1 more source

The importance of gene polymorphism in familial inheritance of endometriosis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single‐nucleotide polymorphism (SNP) array. Methods Patients aged 18–45 who were diagnosed histopathologically with endometriosis were included in the study.
Hale Goksever Celik, Candan Eker, Berivan Guzelbag, Ercan Bastu, Tuba Gunel   +4 more
wiley   +1 more source