Results 41 to 50 of about 2,488,617 (191)

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland, Amber Nakar Weinstein, Eric C. Kao, Xiaonan Zhao, Monika Weisz‐Hubshman   +4 more
wiley   +1 more source

A Rare Case Of Fallopian Tube Cancer [PDF]

, 2008
Fallopian tube carcinoma is a very rare malignancy and we report a case of stage IIC primary fallopian tube ...
Panpalia, Madhavi, Madhavi Panpalia, Roychowdhury, Joydeb, Joydeb Roychowdhury   +3 more
core  

Bioinformatics and system biology approaches to identify molecular pathogenesis of polycystic ovarian syndrome, type 2 diabetes, obesity, and cardiovascular disease that are linked to the progression of female infertility

Informatics in Medicine Unlocked, 2022
Female infertility may be caused by several medical conditions and environmental factors that induce fallopian tube damage or hormonal difficulties. Several metabolic comorbidities like polycystic ovarian syndrome (PCOS), type 2 diabetes (T2D), obesity ...
Md Arju Hossain, Md Al Amin, Md Imran Hasan, Md Sohel, Md Akash Ahammed, S.M. Hasan Mahmud, Md Rezanur Rahman, Md Habibur Rahman   +7 more
doaj   +1 more source

How the HTAR will contribute to a value‐based decision‐making for medicinal products across the EU

British Journal of Clinical Pharmacology, EarlyView.
The European Union Health Technology Regulation 2021/2282 (HTAR) introduces joint assessment of health technologies (including medicinal products and medical devices) across EU Member States. It was signed into law in 2021 and came into full force in January 2025.
Roisin Adams, Michal Stanak
wiley   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Primary Fallopian Tube Carcinoma [PDF]

, 2011
Primary Fallopian Tube Carcinoma (PFTC) is rare and accounts for about 0.3% of all gynecologic cancers. Less than 1500 cases have been reported in the literature.
K, Balaiah, Shetty, Prasad K, S, Gnana Prakash, Balaiah K, Gnana Prakash S, Bafna UD, Bafna, UD, Prasad K Shetty   +7 more
core  

Low‐Grade Serous Carcinoma in Association With Endosalpingiosis in a Cervical Lymph Node: A Case Report and Literature Review

Diagnostic Cytopathology, EarlyView.
ABSTRACT Endosalpingiosis is a benign Müllerian inclusion that rarely involves supradiaphragmatic lymph nodes. Malignant transformation in the setting of nodal endosalpingiosis is exceptional. We report a case of low‐grade serous carcinoma arising in a cervical lymph node in the setting of endosalpingiosis in a 41‐year‐old woman presenting with Horner ...
Nyein Nyein Htun, Nour Sneige
wiley   +1 more source

High‐grade serous peritoneal cancer follows a high stromal response signature and shows worse outcome than ovarian cancer

Molecular Oncology, 2021
In the era of personalized medicine, where transition from organ‐based to individualized genetic diagnosis takes place, the tailoring of treatment in cancer becomes increasingly important.
Francis Jacob, Rosa Lina Marchetti, André B. Kind, Kenneth Russell, Andreas Schoetzau, Viola A. Heinzelmann‐Schwarz   +5 more
doaj   +1 more source

Cross‐Regulation Between DNA Methylation and Circadian Clock Reprogramming in Ovarian Cancer: Mechanistic Insights, Biomarker Potential, and Therapeutic Implications

International Journal of Cancer, EarlyView.
ABSTRACT Early diagnosis remains challenging, recurrence rates remain high, and platinum resistance frequently develops in ovarian cancer (OC), collectively representing major barriers to long‐term patient survival. DNA methylation (DNAm), as a relatively stable yet dynamically modifiable epigenetic signature, can capture alterations in tumor states ...
Min Xing, Chang Zhou, Yi Tang, Shuhui Xu, Shasha Zhou, Weiai Liu, Huiping Liu   +6 more
wiley   +1 more source

Leiomyoma and leiomyoma cellulare of the fallopian tube: review of the literature and case reports

, 2016
Introduction: Leiomyoma of the fallopian tube is extremely rare, and its version – leiomyoma cellulare (LC) of the fallopian tube is absolutely unique.
Dobrosława L. Sikora-Szczęśniak
core   +1 more source