Results 81 to 90 of about 15,400 (217)

Remarks on Tubercular Disease of the Fallopian Tube, with Analysis of Eight Cases. [PDF]

BJOG: An International Journal of Obstetrics & Gynaecology, 1905
n ...
openaire   +1 more source

Mutational Signature‐Based Biomarker for Phase II Trial of Olaparib Maintenance in Advanced High‐Grade Ovarian Cancer

Cancer Science, EarlyView.
A whole‐exome sequencing–based mutational signature biomarker (MSBM) identified an HRD‐enriched population in advanced ovarian cancer. In a phase II trial, olaparib maintenance suggested clinically meaningful PFS benefit without bevacizumab, supporting MSBM as a complementary HRD assessment approach.
Katsutoshi Oda, Daisuke Shintani, Akira Nishijima, Mayuyo Mori, Kazuyoshi Kato, Shoji Nagao, Noriomi Matsumura, Masahiro Kagabu, Masataka Takenaka, Kosuke Yoshihara, Yosuke Konno, Junzo Hamanishi, Sho Sato, Shiro Takamatsu, Keiko Ueda, Kosuke Kashiwabara, Takashi Aoki, Kunihiro Nishimura, Kenji Tatsuno, Hiroyuki Aburatani, Kosei Hasegawa   +20 more
wiley   +1 more source

Unveiling ectopic pregnancy in Mosul city (Iraq): critical insights into symptoms, risk profiles, imaging findings, and treatment outcomes

Mìžnarodnij Endokrinologìčnij Žurnal
Background. Ectopic pregnancy (EP) is a leading obstetric emergency and a life-threatening condition that usually defines the implantation of a fertilized ovum outside of the uterine cavity, most frequently occurred in the fallopian tubes.
Hiba Ahmed Suhail, Abeer Wali Ahmed, Suha Mudhafar Abdullah, Zeena Salih Mohammed   +3 more
doaj   +1 more source

Recent Advances in Identifying Biomarkers and High-Affinity Aptamers for Gynecologic Cancers Diagnosis and Therapy

Journal of Analytical Methods in Chemistry, 2019
Cancer is the uncontrollable abnormal division of cell growth, caused due to the varied reasons. Cancer can be expressed in any part of the body, and it is one of the death-causing diseases. Human reproductive organs are commonly damaged by cancer.
Xiaoqun Ma, Thangavel Lakshmipriya, Subash C. B. Gopinath   +2 more
doaj   +1 more source

Primary Fallopian Tube Carcinoma Arising in the Setting of Chronic Pelvic Inflammatory Disease [PDF]

Case Reports in Medicine, 2014
Primary fallopian tube cancer (PFTC) is a rare gynaecological malignancy, clinically often mistaken for pelvic inflammatory disease or ovarian cancer. Three primary fallopian tube carcinomas, arising in a background of chronic pelvic inflammatory disease (PID), are presented.
openaire   +3 more sources

MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy

Cancer Science, EarlyView.
MTAP deletion creates a therapeutically actionable metabolic vulnerability through MTA accumulation and PRMT5 dependency. This review summarizes the biochemical basis of MTAP‐directed synthetic lethality, emerging PRMT5/MAT2A inhibitors, clinicogenomic features of MTAP‐deleted tumors, and future strategies for precision oncology.
Hiroaki Ikushima, Hidenori Kage
wiley   +1 more source

Infertility registry data of infertile couples in southern Iran: 2017-2022 [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Introduction: Infertility causes serious damage to the reproductive health system. It has been decided that all countries should include infertility in priority programs related to reproductive health.
Maryam Azizi Kutenaee, Nasibeh Roozbeh, Samaneh Dabagh Fekri, Mojdeh Banaei, Amireh Aji, Dina Abadi Bavil   +5 more
doaj   +1 more source

A Practical Treatise on the Diseases of the Uterus. Ovaries, and Fallopian Tubes

The American Journal of the Medical Sciences, 1883
Translation of Traité pratiques des maladies de l'utérus. ; Includes bibliographies. ; Mode of access: Internet.
openaire   +2 more sources

Phase II Trial of Nivolumab in Advanced Solid Tumors Based on Genomic Profiling: BELIEVE Trial (NCCH1901) Subcohort

Cancer Science, EarlyView.
Off‐label nivolumab treatment guided by CGP results was evaluated in 56 patients with advanced solid tumors. TMB‐High was the predominant biomarker leading to nivolumab treatment. Nivolumab showed limited clinical benefit in 50 patients with measurable disease, with an ORR of 16.0%, DCR of 40.0%, median PFS of 2.7 months, and median OS of 7.2 months ...
Masashi Kanai, Kuniko Sunami, Tatsunori Shimoi, Satoshi Nishiwaki, Ichiro Kinoshita, Tetsuhiro Yoshinami, Chigusa Morizane, Yusuke Sato, Toshio Kubo, Mamoru Ito, Hiroshi Nishihara, Toru Mukohara, Hidekazu Shirota, Ryo Ko, Taro Shibata, Manabu Muto, Noboru Yamamoto   +16 more
wiley   +1 more source

Advancing collagen‐related pathology assessment through second‐harmonic generation imaging

Journal of Microscopy, EarlyView.
Abstract Collagen remodelling and dysregulation are the hallmarks of diverse pathological conditions. In this context, second‐harmonic generation (SHG) imaging has emerged as a powerful label‐free modality for assessing collagen. This offers submicron resolution, intrinsic optical sectioning, and deeper imaging capabilities without the need for ...
Jackson Rodrigues, Manikanth Karnati, Gagan Raju, Edwin Pious, Ankur Gogoi, Guan‐Yu Zhuo, Nirmal Mazumder, Fu‐Jen Kao   +7 more
wiley   +1 more source