Results 121 to 130 of about 2,482,501 (258)
Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami +15 more
wiley +1 more source
The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source
Female infertility remains one of the important problems of modern gynecology. The most common form of female infertility is tubal-peritoneal, which develops as a result of inflammatory diseases of the uterine appendages or surgical interventions on the ...
Сергей Валериевич Рыбников +5 more
doaj
The Baboon as a Model to Study Human Health and Complex Disease
Baboons remain underappreciated as models of human biology and disease offering a distinct combination of biological and practical properties. In this review, we evaluate the baboon as a model for human complex diseases and make the case for broader use of baboons in translational research.
Brittany Hazzard, Yoav Gilad
wiley +1 more source
Preoperative diagnosis of Primary Fallopian tube carcinoma [PDF]
Primary Fallopian tube carcinoma is a rare malignancy of the female reproductive tumors, and it is difficult to diagnose in earlier stages. We present herein a case of primary Fallopian tube carcinoma diagnosed preoperatively.
ハバ, レイジ +33 more
core +2 more sources
Laparoscopic Management of Fallopian Tube Prolapse Following an Abdominal Hysterectomy
© 2016 Mary Ann Liebert, Inc.Background: Fallopian-tube prolapse into the vaginal vault is a rare complication of a hysterectomy, with conservation of the fallopian tube and ovaries.
Ozturk, Mustafa +5 more
core +1 more source
ABSTRACT Background While the time burden of cancer care is increasingly recognized in oncology, existing research lacks the granularity needed to identify intervention targets. This study characterized time spent on cancer care at home and in‐clinic, including travel, waiting, and clinical tasks, assessing variations by treatment modality.
Gabrielle B. Rocque +12 more
wiley +1 more source
Age, lifestyle, and disease affect ciliary transport in the human fallopian tube
The synchronized beating of ciliated cells within the human fallopian tube is crucial for the transport of the oocyte and the early embryo. To date, the precise effects of age, lifestyle, and disease on ciliary beating in the human fallopian tube are still unknown.
Neville, Caoimhe +6 more
openaire +3 more sources
PD‐L1 in Ovarian Cancer: Immune Evasion, Tumor‐Intrinsic Signaling, and Chemoresistance
The “Dual Shield” model of PD‐L1 in ovarian cancer. On the outside, PD‐L1 engages PD‐1 to inactivate T cells and drive immune evasion (immune shield). Inside the tumor cell, PD‐L1 activates AKT–mTOR, enhances DNA repair, rewires metabolism, supports autophagy, and enforces stemness programs—collectively creating a chemoresistance shield.
Zhiyang Xu +3 more
wiley +1 more source
Synchronous Vaginal and Liver Metastases in Rectosigmoid Cancer: Case Report and Literature Review
ABSTRACT Vaginal metastasis from colorectal cancer is extremely rare. We report the case of a 58‐year‐old postmenopausal woman with rectosigmoid adenocarcinoma and synchronous liver and vaginal metastases who initially presented with gastrointestinal symptoms followed by vaginal bleeding.
Tamader Alyaarabi +7 more
wiley +1 more source

