Results 111 to 120 of about 949,682 (362)

Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation

open access: yesNature Communications, 2019
Chronic infections of the fallopian tubes with Chlamydia trachomatis can cause scarring and infertility. Here, the authors show that the pathogen alters stem cell differentiation and DNA methylation in human fallopian tube organoids, suggesting a ...
Mirjana Kessler   +11 more
doaj   +1 more source

Inflammation is a key contributor to ovarian cancer cell seeding. [PDF]

open access: yes, 2018
The incidence of ovarian cancer dramatically increases in early menopause but the factors contributing to cancer onset are unclear. Most ovarian cancers originate in the fallopian tube with subsequent implantation of malignant cells into the ovary ...
Jia, Dongyu   +3 more
core   +1 more source

Lactate inhibits glucose‐induced zigzag motility and enhances linear motility in bull spermatozoa by suppressing glycolysis

open access: yesAndrology, EarlyView.
Abstract Background Energy metabolism and substrate balance are critical determinants of sperm motility and fertility. Linear motility is necessary for sperm forward movement, whereas hyperactivated motility is a prerequisite for fertilization. The preference of metabolic pathways depends on substrate availability which controls sperm motility. However,
Md Faizul Hossain Miraz   +4 more
wiley   +1 more source

Refining Tumor Mutational Burden as a Predictive Biomarker for Pembrolizumab: A Real‐World Analysis in Japanese Patients

open access: yesCancer Science, EarlyView.
In this study, we investigated the predictive value of tumor mutational burden (TMB) for assessing the efficacy of pembrolizumab in a Japanese cohort. We analyzed real‐world data from 63,952 patients registered in the C‐CAT database who underwent comprehensive genomic profiling, and evaluated the therapeutic efficacy of pembrolizumab in 1899 of these ...
Tomoyo Yasuda   +7 more
wiley   +1 more source

Magnetic resonance imaging in diagnosis of serous adenocarcinoma of fallopian tubes: a case report

open access: yesDigital Diagnostics
Serous adenocarcinoma of fallopian tubes is an extremely rare and difficult to diagnose type of cancer of the female reproductive system. This condition is often asymptomatic or has a non specific clinical presentation including serosanguineous vaginal ...
Oleg I. Mynko   +5 more
doaj   +1 more source

Exploring the presence of markers of decidualization in the fallopian tubes: a systematic review. [PDF]

open access: yesBiol Reprod, 2023
Aljassim F   +6 more
europepmc   +1 more source

Unraveling the Genetic Mysteries of Müllerian Anomalies: Research Approaches and Clinical Significance

open access: yesClinical Genetics, EarlyView.
This review primarily summarizes the genetic defects in Müllerian anomalies, the tools used to validate these genetic defects, and the future clinical significance of identifying the precise genetic etiology of Müllerian anomalies. ABSTRACT Müllerian anomalies are a collection of heterogeneous anatomical disorders of the female genital tract that ...
Jingfang Li   +5 more
wiley   +1 more source

Mycoplasmateceae species are not found in Fallopian tubes of women with tubo-peritoneal infertility

open access: yesBrazilian Journal of Infectious Diseases
BACKGROUND: The role of mycoplasmas on the development and sequelae of pelvic inflammatory disease remains controversial. The objective of the present study is to correlate directly the presence of Mycoplasmateceae through polimerase chain reaction (PCR)
Alberto Costoya   +7 more
doaj   +1 more source

Mature Cystic Teratoma at Fallopian Tubes: A Case Series. [PDF]

open access: yesJNMA J Nepal Med Assoc, 2023
Kayastha S   +5 more
europepmc   +1 more source

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