Results 111 to 120 of about 203,725 (239)

Cross‐Regulation Between DNA Methylation and Circadian Clock Reprogramming in Ovarian Cancer: Mechanistic Insights, Biomarker Potential, and Therapeutic Implications

open access: yesInternational Journal of Cancer, Volume 160, Issue 1, Page 7-23, 1 January 2027.
ABSTRACT Early diagnosis remains challenging, recurrence rates remain high, and platinum resistance frequently develops in ovarian cancer (OC), collectively representing major barriers to long‐term patient survival. DNA methylation (DNAm), as a relatively stable yet dynamically modifiable epigenetic signature, can capture alterations in tumor states ...
Min Xing   +6 more
wiley   +1 more source

Which mode and potency of electrocoagulation yields the Smallest Unobstructed Area of the Fallopian Tubes?

open access: yes, 2018
Objective To determine which mode and potency of electrocoagulation, using a modern electrosurgical generator, yields the smallest unobstructed area of the Fallopian tubes.
Lúcia Kliemann   +4 more
core   +2 more sources

Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation

open access: yesNature Communications, 2019
Chronic infections of the fallopian tubes with Chlamydia trachomatis can cause scarring and infertility. Here, the authors show that the pathogen alters stem cell differentiation and DNA methylation in human fallopian tube organoids, suggesting a ...
Mirjana Kessler   +11 more
doaj   +1 more source

Low‐Grade Serous Carcinoma in Association With Endosalpingiosis in a Cervical Lymph Node: A Case Report and Literature Review

open access: yesDiagnostic Cytopathology, Volume 54, Issue 12, Page E319-E323, December 2026.
ABSTRACT Endosalpingiosis is a benign Müllerian inclusion that rarely involves supradiaphragmatic lymph nodes. Malignant transformation in the setting of nodal endosalpingiosis is exceptional. We report a case of low‐grade serous carcinoma arising in a cervical lymph node in the setting of endosalpingiosis in a 41‐year‐old woman presenting with Horner ...
Nyein Nyein Htun, Nour Sneige
wiley   +1 more source

Down-Regulation of Cilia-Localized IL-6R{alpha} by 17{beta}-Estradiol in Mouse and Human Fallopian Tubes

open access: yes, 2009
The action of Interleukin-6 (IL-6) impacts female reproduction. Although IL-6 was recently shown to inhibit cilia activity in human fallopian tubes in vitro, the molecular mechanisms underlying IL-6 signaling to tubal function remain elusive.
Weijdegård, Birgitta,   +21 more
core   +1 more source

Additional sectioning and AI‐assisted diagnosis reveal underdiagnosis of serous (pre)malignancies in fallopian tube specimen from BRCA1/2 carriers

open access: yesHistopathology, Volume 89, Issue 6, Page 964-974, December 2026.
This paper shows that deeper sections reveal additional STICs and HGSCs in risk‐reducing salpingo‐oophorectomy specimens of patients who did not have a STIC or HGSC diagnosis but did develop peritoneal HGSC 10 years after surgery. This adds to the premise that HGSC originates in the fallopian tube.
Anouk B Bouwmeester   +17 more
wiley   +1 more source

Magnetic resonance imaging in diagnosis of serous adenocarcinoma of fallopian tubes: a case report

open access: yesDigital Diagnostics
Serous adenocarcinoma of fallopian tubes is an extremely rare and difficult to diagnose type of cancer of the female reproductive system. This condition is often asymptomatic or has a non specific clinical presentation including serosanguineous vaginal ...
Oleg I. Mynko   +5 more
doaj   +1 more source

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 11, Page 2519-2524, November 2026.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland   +4 more
wiley   +1 more source

Primary neuroendocrine carcinoma of the fallopian tube: A case report

open access: yes, 2004
Neuroendocrine carcinomas arise from Kulchitsky cells and are frequently seen in gastrointestinal tract and lungs. But they are unusual in gynecology practice.
Salman, MC   +7 more
core   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3902-3913, November 2026.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub   +3 more
wiley   +1 more source

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