Results 111 to 120 of about 194,055 (249)
The Journal of Physiology, EarlyView.Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington +4 more
wiley +1 more source
Oestrogen modulates stress‐induced vagally‐dependent gastric responses to oxytocin
The Journal of Physiology, EarlyView.Abstract figure legend In female rats, PVNCRF‐DMV neurons and DMV CRF1 receptors are tonically active, allowing oxytocin (OXT) to modulate inhibitory GABAergic transmission to DMV neurons. Parasympathetic control of gastric functions involves engagement of non‐adrenergic non‐cholinergic vagal efferent pathways, but recruitment of distinct pathways ...
Ruchi Bhagat +2 more
wiley +1 more source
International Journal of Cancer, Volume 159, Issue 7, Page 1735-1749, 1 October 2026.The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg +9 more
wiley +1 more source
Fallopian Tubes Intraepithelial Lesions Developed In Breast, Ovarian Or Uterine Body Cancer Patients [PDF]
, 2018 Aim and objectives. Identify and evaluate lesions developed in fallopian tubes in breast, ovarian and uterine body cancer patients. Evaluate influence of these cancers on fallopian tube lesion development. Methods.
Kilimaitė, Evelina
core
, 2010 Hysterosalpingography is the primary technique in providing coarse information on the morphology of endometrial cavity and fallopian tubes. In this preliminary study, 64-detector computed tomography was used for three-dimensional imaging of endometrium ...
Tagluk, M. Emin +3 more
core +1 more source
International Journal of Cancer, Volume 159, Issue 7, Page 1588-1601, 1 October 2026.ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley +8 more
wiley +1 more source
The evolving role of immunotherapy in ovarian cancer
Cancer, Volume 132, Issue 18, 15 September 2026.Abstract Ovarian cancer remains a major cause of gynecologic cancer mortality; and, although immune checkpoint inhibitors have transformed treatment in other solid tumors, their activity in ovarian cancer has been limited by tumor heterogeneity, an immunosuppressive tumor microenvironment, and the lack of robust predictive biomarkers.
Ana Carolina Veneziani +2 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, Volume 20, Issue 9, Page 2262-2279, September 2026.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, Volume 20, Issue 9, Page 2323-2339, September 2026.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Molecular Oncology, Volume 20, Issue 9, Page 2135-2162, September 2026.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source