Results 51 to 60 of about 22,576 (166)

A New Methodology to Assess Fallopian Tubes Microbiota and Its Impact on Female Fertility. [PDF]

open access: yesDiagnostics (Basel), 2022
Vitale SG   +5 more
europepmc   +1 more source

Unraveling the Genetic Mysteries of Müllerian Anomalies: Research Approaches and Clinical Significance

open access: yesClinical Genetics, Volume 109, Issue 4, Page 615-629, April 2026.
This review primarily summarizes the genetic defects in Müllerian anomalies, the tools used to validate these genetic defects, and the future clinical significance of identifying the precise genetic etiology of Müllerian anomalies. ABSTRACT Müllerian anomalies are a collection of heterogeneous anatomical disorders of the female genital tract that ...
Jingfang Li   +5 more
wiley   +1 more source

Using Genomic Variation to Distinguish Ovarian High-Grade Serous Carcinoma from Benign Fallopian Tubes. [PDF]

open access: yesInt J Mol Sci, 2022
Gonzalez-Bosquet J   +7 more
europepmc   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1617-1627, 15 March 2026.
What's new? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman   +15 more
wiley   +1 more source

Doppel as an early‐stage biomarker promoting EMT and dissemination in ovarian cancers

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1755-1768, 15 March 2026.
What's new? Existing biomarkers for ovarian cancer (OC) lack the sensitivity and specificity needed to consistently distinguish the malignancy from non‐ovarian influences and other cancers. Here, the authors explored the ability of the prion‐like protein Doppel, normally found in the male testes, to detect OC.
Zulfikar Azam   +18 more
wiley   +1 more source

Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq. [PDF]

open access: yesDev Cell, 2022
Ulrich ND   +16 more
europepmc   +1 more source

Tumor‐Infiltrating Nociceptor Neurons in Ovarian Cancer Treatment Resistance

open access: yesAdvanced Biology, Volume 10, Issue 3, March 2026.
This study shows that high‐grade serous ovarian carcinomas (HGSOC) are significantly more innervated than the other histological subtypes. HGSOC small extracellular vesicles (sEVs) promote neurite outgrowth in vitro. Analysis of pre‐ and post‐treatment HGSOC samples shows that innervation increases post‐chemotherapy.
Allison Jorgensen   +12 more
wiley   +1 more source

Diameter Estimation of Fallopian Tubes Using Visual Sensing. [PDF]

open access: yesBiosensors (Basel), 2021
Hajiyavand AM, Graham MJ, Dearn KD.
europepmc   +1 more source

Targeting Autophagy in Ovarian Cancer: The Emerging Role of Ginsenosides

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Ovarian cancer, the third most prevalent gynecological malignancy, is frequently diagnosed at an advanced stage owing to its asymptomatic early progression. Despite the application of conventional therapies, clinical management remains limited by adverse effects and the development of drug resistance.
Yuxin Guo   +4 more
wiley   +1 more source

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