Results 71 to 80 of about 945,883 (350)

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, EarlyView.
What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Особливості експресії маркера проліферації Кі-67 у тканині первинного раку маткових труб [PDF]

, 2016
Метою дослідження стало визначення особливості експресії маркера проліферації Кі-67 у тканині первинного раку маткових труб за допомогою імуногістохімічного дослідження із використанням кролячих моноклональних антитіл до білка Кі-67 (клон SP6 ...
Hyriavenko, Nataliia Ivanivna, Lyndin, Mykola Serhiiovych, Romaniuk, Anatolii Mykolaiovych, Sikora, Vladyslav Volodymyrovych, Zolotarova, Alina Viktorivna, Гирявенко, Наталья Ивановна, Гирявенко, Наталія Іванівна, Золотарева, Алина Викторовна, Золотарьова, Аліна Вікторівна, Линдін, Микола Сергійович, Лындин, Николай Сергеевич, Романюк, Анатолий Николаевич, Романюк, Анатолій Миколайович, Сикора, Владислав Владимирович, Сікора, Владислав Володимирович   +14 more
core  

Doppel as an early‐stage biomarker promoting EMT and dissemination in ovarian cancers

International Journal of Cancer, EarlyView.
What's New? Existing biomarkers for ovarian cancer (OC) lack the sensitivity and specificity needed to consistently distinguish the malignancy from non‐ovarian influences and other cancers. Here, the authors explored the ability of the prion‐like protein Doppel, normally found in the male testes, to detect OC.
Zulfikar Azam, Xiaojun Zhang, Riajul Wahab, Md Mahedi Hasan, Shivaniben Dhadhal, Bowon Kang, Md Mynul Hassan, Mazharul Karim, Jeong Uk Choi, Muhit Rana, Jian‐Ying Zhang, Sourav Roy, Youngro Byun, In‐San Kim, Jae Yun Song, Eugene P. Toy, Sireesha Y. Reddy, Farzana Alam, Taslim A. Al‐Hilal   +18 more
wiley   +1 more source

Fallopian tube origin of supposed ovarian high-grade serous carcinomas

Clinics, 2011
INTRODUCTION: Serous carcinomas are the most frequent histologic type of ovarian and peritoneal cancers, and can also be detected in the endometrium and fallopian tubes.
Patricia Martini Diniz, Jesus Paula Carvalho, Edmund Chada Baracat, Filomena M Carvalho   +3 more
doaj  

Comparison of Immediate and Delayed Transfer of Micro- Injected Oocytes into Fallopian Tubes: A Prospective, Randomized Clinical Trial [PDF]

International Journal of Fertility and Sterility, 2008
Background Transfer of micro-Injected oocytes into fallopian tubes is an alternative procedure for IVF-ET with a similar success rate. This could be either done immediately after ovum pick-up microinjected oocytes intrafallopian transfer (MIFT) or after ...
Ashraf Alleyassin, Azita Mahmoodan, Marzieh Aghahosseini, Leili Safdarian, Hojatollah Saeidi Saeidabadi   +4 more
doaj   +1 more source

Brave Sperm and Demure Eggs: Fallopian Gender Politics on YouTube [PDF]

, 2015
A narrative analysis of videos of human conception from medical and nonmedical sources aired in the democratic space of YouTube finds that stereotypical gender roles are consistently assigned to cellular behavior.
Nettleton, Pamela Hill
core   +1 more source

Detecting TP53 mutations in paired liquid and tissue biopsies from patients with high‐grade serous ovarian carcinoma

International Journal of Cancer, EarlyView.
What's New? High‐grade serous ovarian carcinoma is often diagnosed at advanced stages due to non‐specific symptoms and the lack of reliable screening methods. This proof‐of‐concept study introduces a novel TP53 mutation panel using unique molecular identifier‐based next‐generation sequencing for sensitive detection of high‐grade serous ovarian ...
Amanda Olsson Widjaja, Peter Micallef, Maria Lycke, Tobias Österlund, Manuel Luna Santamaría, Julia Hedlund Lindberg, Therese Carlsson, Ulf Gyllensten, Anders Ståhlberg, Benjamin Ulfenborg, Anna Linder, Karin Sundfeldt   +11 more
wiley   +1 more source

Histomorphology of fallopian tubes in ectopic pregnancy

Archives of Medicine and Health Sciences, 2016
Background: Ectopic pregnancy can present as an acute life-threatening emergency when it ruptures and accounts for about 10% of all maternal mortalities. The fallopian tube is the most common site for ectopic pregnancy (90–95%).
Savithri Ravindra, Sruthi Prasad, Belur Venugopal Suguna   +2 more
doaj   +1 more source

Spontaneous hemoperitoneum in a 29‐week pregnancy with a history of endometriosis: A case report and review of the literature

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 31-37, April 2025.
Abstract Spontaneous hemoperitoneum in pregnancy (SHIP) is defined as sudden, nontraumatic intraperitoneal bleeding that occurs during pregnancy or up to 42 days postpartum. The incidence ranges between 4 and 4.9 per 100 000 births. Although seen rarely, it is associated with perinatal morbidity and mortality due to maternal hemodynamic instability ...
Shamsi Mehdiyev, Fatma Basak Tanoglu, Esma Demir Altuncu, Engin Oral   +3 more
wiley   +1 more source

Persistent mullerian duct syndrome

Indian Journal of Radiology and Imaging, 2010
Persistent Mullerian duct syndrome (PMDS) is a rare form of internal male pseudohermaphroditism in which Mullerian duct derivatives are seen in a male patient. This syndrome is characterized by the persistence of Mullerian duct derivatives (i.e.
Divya Renu, B Ganesh Rao, K Ranganath
doaj   +3 more sources