Results 101 to 110 of about 736,514 (317)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Guideline‐directed medical therapy implementation during hospitalization for cardiogenic shock

ESC Heart Failure
Aims Despite significant morbidity and mortality, recent advances in cardiogenic shock (CS) management have been associated with increased survival. However, little is known regarding the management of patients who survive CS with heart failure (HF) with
Matthew G. Dimond, Carolyn M. Rosner, Seiyon Ben Lee, Unique Shakoor, Taraneh Samadani, Wayne B. Batchelor, Abdulla A. Damluji, Shashank S. Desai, Kelly C. Epps, M. Casey Flanagan, Hala Moukhachen, Anika Raja, Matthew W. Sherwood, Ramesh Singh, Palak Shah, Daniel Tang, Behnam N. Tehrani, Alexander G. Truesdell, Karl D. Young, Mona Fiuzat, Christopher M. O'Connor, Shashank S. Sinha, Mitchell A. Psotka   +22 more
doaj   +1 more source

Investigating the relationship between hoof, liver, and heart abnormalities in grain-fed beef cattle (Bos taurus) <30 months at slaughter

Frontiers in Animal Science
Hoof abnormalities, liver abscesses, and congestive heart failure (CHF) are animal welfare concerns that have increased in fed cattle. Our objective was to determine whether relationships between these issues exist in fed cattle at slaughter.
Emma M. Hamilton, Karly N. Anderson, Karly N. Anderson, Ashlynn A. Kirk, Ashlynn A. Kirk, Kurt D. Vogel, Kurt D. Vogel, Temple Grandin   +7 more
doaj   +1 more source

Cuyahoga Falls High School, Cuyahoga Falls

, 2023
Postcard showing the red brick building of the Cuyahoga Falls High School.

core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Enhancing casein micelle dissociation in diluted skim milk systems using combined processing techniques

Journal of Dairy Science
: The present work aims to evaluate the dissociation of casein micelles in diluted skim milk (SM) systems after undergoing solvent- or emulsifying salt-based dissociation coupled with ultra-high-pressure homogenization (UHPH).
D.R. Stroinski, K. Petersen, G.E. Lewis
doaj   +1 more source

Hydraulic Model Studies of St. Anthony Falls Spillway

, 1952
In the spring of 1952, the maximum measured discharge of the Mississippi River occurred at the St. Anthony Falls Dam of the Northern States Power Company at Minneapolis, Minnesota.
Straub, Lorenz G.
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Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Falls Hollow Staybolt Co. timing machine, Cuyahoga Falls

, 2023
Falls Hollows Staybolt Co. factory interior showing the timing machine at the left."Grandpa Gartley at his timing machine./ Girls Mae Hefferman/Mary Fitzgarld/ Frank Harry Grandpa's Helper/ Robert Rord the Boss/ Falls Hollow Stay Bolt (Behind Falls ...

core  

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source