Results 61 to 70 of about 63,938 (281)

PowerFDNet: Deep Learning-Based Stealthy False Data Injection Attack Detection for AC-Model Transmission Systems

IEEE Open Journal of the Computer Society, 2022
Smart grids are vulnerable to stealthy false data injection attacks (SFDIAs), as SFDIAs can bypass residual-based bad data detection mechanisms. Methods based on deep learning technology have shown promising accuracy in the detection of SFDIAs.
Xuefei Yin, Yanming Zhu, Yi Xie, Jiankun Hu   +3 more
doaj   +1 more source

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Privacy-Preserving Data Aggregation against False Data Injection Attacks in Fog Computing [PDF]

Sensors, 2018
As an extension of cloud computing, fog computing has received more attention in recent years. It can solve problems such as high latency, lack of support for mobility and location awareness in cloud computing. In the Internet of Things (IoT), a series of IoT devices can be connected to the fog nodes that assist a cloud service center to store and ...
Yinghui Zhang, Jiangfan Zhao, Dong Zheng, Kaixin Deng, Fangyuan Ren, Xiaokun Zheng, Jiangang Shu   +6 more
openaire   +3 more sources

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

One Breaker is Enough: Hidden Topology Attacks on Power Grids

, 2015
A coordinated cyber-attack on grid meter readings and breaker statuses can lead to incorrect state estimation that can subsequently destabilize the grid. This paper studies cyber-attacks by an adversary that changes breaker statuses on transmission lines
Baldick, Ross, Deka, Deepjyoti, Vishwanath, Sriram   +2 more
core   +1 more source

B4GALNT4‐Mediated Glycosylation of PDK1 Activates the PI3K‐AKT Signaling Pathway to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
This study identifies B4GALNT4 as a key driver of prostate cancer (PCa). It shows that B4GALNT4 glycosylates PDK1 protein at the N531 site, which stabilizes the PDK1 and constitutively activates the PI3K‐AKT pathway. This mechanism promotes tumor cell proliferation, migration, and invasion. The findings establish the B4GALNT4‐PDK1 glycosylation axis as
Shaoqin Jiang, Mengqiang Li, Qingfu Su, Ruiling Dou, Shaoshan Lin, Jili Zhang, Xiaochen Sun, Haolan Yu, Wei Bao, Min Qu, Yan Wang, Chenghua Yang, Xu Gao   +12 more
wiley   +1 more source

Tuning Windowed Chi-Squared Detectors for Sensor Attacks

, 2017
A model-based windowed chi-squared procedure is proposed for identifying falsified sensor measurements. We employ the widely-used static chi-squared and the dynamic cumulative sum (CUSUM) fault/attack detection procedures as benchmarks to compare the ...
aström, chen, cárdenas, gustafsson, lancaster, li, murguia   +6 more
core   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Fast Sequence Component Analysis for Attack Detection in Synchrophasor Networks [PDF]

, 2015
Modern power systems have begun integrating synchrophasor technologies into part of daily operations. Given the amount of solutions offered and the maturity rate of application development it is not a matter of "if" but a matter of "when" in regards to ...
Barella, Richard, Bass, Robert B., Cotilla-Sanchez, Eduardo, Landford, Jordan, Meier, Rich, Wallace, Scott, Zhao, Xinghui   +6 more
core   +2 more sources