Results 141 to 150 of about 385,160 (293)

FastLSU: A Linear Implementation for Controlling the False Discovery Rate

open access: yes, 2016
Large-scale hypothesis testing is an important experimental procedure in the field of bioinformatics. Often times, researchers would like to control the rate of false positives that appear in their experiments.
Ceme, Mckervin
core  

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

Using expert knowledge with control of false discovery rate to select regressors for prediction of soil properties

open access: yes, 2007
Soil scientists often have many covariates that they can use to predict soil properties by regression. They are ill-advised to use all available covariates uncritically, but methods for selection (whether informal or formal) that depend on data for both ...
Webster, R.   +2 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Benchmarking Pretrained Models for Speech Emotion Recognition: A Focus on Xception

open access: yesComputers
Speech emotion recognition (SER) is an emerging technology that utilizes speech sounds to identify a speaker’s emotional state. Computational intelligence is receiving increasing attention from academics, health, and social media applications.
Ahmed Hassan   +4 more
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Bayesian False Discovery Rate Wavelet Shrinkage: Theory and Applications

open access: yes, 2008
. Statistical inference in the wavelet domain remains vibrant area of contemporary statistical research because desirable properties of wavelet representations and the need of scientific community to process, explore, and summarize massive data sets ...
Yoon Young Jung   +3 more
core   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Is a score enough? Pitfalls and solutions for AI severity scores

open access: yesEuropean Radiology Experimental
Severity scores, which often refer to the likelihood or probability of a pathology, are commonly provided by artificial intelligence (AI) tools in radiology.
Michael H. Bernstein   +5 more
doaj   +1 more source

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